Early Intervention of High Tension in the Pancreatic Duct on the Outcome of Severe Biliary Pancreatitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-01

Study Completion Date

2021-06-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The investigators hypothesized that naso-pancreatic duct suction could benefit for patients with severe biliary pancreatitis undergoing ERCP. So, the investigators designed this experiment to verify it.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Anatomy of Major Duodenal Papilla on the Difficulty of Cannulation During Endoscopic Retrograde Cholangiopancreatography

NCT03550768

Pancreaticobiilary Diseases Endoscopic Retrograde Cholangiopancreatography

COMPLETED

Nasogastric Tube in Pancreatic Surgery

NCT03462602

Nasogastric Tube Decompression Pancreatic Surgery

UNKNOWN NA

Pancreaticoduodenectomy With or Without Preoperative Hyperbaric Oxygen Therapy

NCT02575014

Periampullary Tumor Common Bile Duct Neoplasms Duodenal Neoplasms

UNKNOWN NA

Risk Factors for Post-ESWL and Post-ERCP Pancreatitis

NCT04619511

Chronic Pancreatitis Risk Factors ERCP +1 more

COMPLETED

Early Versus Standard Endoscopic Interventions for Peripancreatic Fluid Collections

NCT05281458

Acute Pancreatitis Peripancreatic Fluid Collections Endoscopic Ultrasound-Guided Drainage +1 more

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This project intends to conduct treatment based on different interventions for enrolled subjects according to international and domestic standardized treatment procedures, including 1.ERCP stone extraction, duodenal papillary pressure measurement, bile duct pressure measurement, and nasal bile duct placement; 2.ERCP+ duodenal papillary pressure measurement, biliopancreatic duct pressure measurement + nasopancreatic duct + determine whether nasopancreatic duct negative pressure attraction.Compare the advantages of two different treatment methods.This paper attempts to explore new treatment methods that are more conducive to the rehabilitation of patients and provides an important preliminary research basis for the future clinical application of standardized treatment.

Patients from the people's hospital of Wuhan university were recruited and selected into groups. The incidence, recurrence rate, operation time and hospital stay of the two independent samples will be compared.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

ERCP

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Nasobiliary drainage

Group Type ACTIVE_COMPARATOR

control

Intervention Type PROCEDURE

Treatment was randomly selected according to preoperative grouping. After ERCP, nasobiliary drainage was chosen as treatment。

Naso-pancreatic drainage(negative pressure)

Group Type EXPERIMENTAL

experiment

Intervention Type PROCEDURE

Treatment was randomly selected according to preoperative grouping. After ERCP, naso-pancreatic drainage was chosen as treatment。

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

experiment

Treatment was randomly selected according to preoperative grouping. After ERCP, naso-pancreatic drainage was chosen as treatment。

Intervention Type PROCEDURE

control

Treatment was randomly selected according to preoperative grouping. After ERCP, nasobiliary drainage was chosen as treatment。

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Naso-pancreatic duct negative pressure attraction naso-biliary drinage

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Ages 16 to 75. Apach-ii score of patients diagnosed with pancreatitis was greater than 8 points.

Liver function can be damaged. Elevated indicators of pancreatitis (hematuria amylase, lipase). Identify patients with biliary tract infection or obstruction.

Exclusion Criteria

Older than 75 or younger than 16. The duration of admission was more than 72 hours. Gastrointestinal obstruction endoscopy cannot be operated. Patients with duodenoscopy contraindications.

Minimum Eligible Age

16 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No