Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
2 participants
INTERVENTIONAL
2020-10-15
2021-08-04
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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Healthy controls
* No co-morbid medical or psychiatry diagnoses
* No family history of mental illness
* No current medication use
* Non-smoking
Light intensity, ~30 lux
\~30 lux compared to very dim light baseline condition \<1 lux
Baseline light intensity, <1 lux
Very dim light condition
Bipolar I disorder
* Clinical diagnosis of Bipolar I disorder
* Can be (not required, not exclusionary) taking lithium and/or sodium valproate and/or antidepressants
* Can be (not required, not exclusionary) light smokers
Light intensity, ~30 lux
\~30 lux compared to very dim light baseline condition \<1 lux
Baseline light intensity, <1 lux
Very dim light condition
Interventions
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Light intensity, ~30 lux
\~30 lux compared to very dim light baseline condition \<1 lux
Baseline light intensity, <1 lux
Very dim light condition
Eligibility Criteria
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Inclusion Criteria
* Appropriate sleep schedules according to study staff. Sleep schedule is self-reported and confirmed through a sleep diary
* Healthy eyes as ascertained by eye exam at University of Michigan Kellogg Eye Center
* Willing and able to maintain stable sleep schedule during study.
* Participants will be breathalyzed and undergo urine drugs screens at every lab visit
* Acknowledge and understand that participants cannot drive themselves home after certain lab visits. Note that the research team will provide a travel stipend of $10 per visit to offset potential rideshare/taxi costs
Exclusion Criteria
18 Years
45 Years
ALL
Yes
Sponsors
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University of Michigan
OTHER
Responsible Party
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Helen Burgess
Professor of Psychiatry
Principal Investigators
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Helen Burgess, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Michigan
Locations
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University of Michigan
Ann Arbor, Michigan, United States
Countries
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Other Identifiers
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HUM00173528
Identifier Type: -
Identifier Source: org_study_id
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