Serratus Anterior Plane Block Versus Intercostal Nerve Block for Postoperative Analgesia

NCT ID: NCT04250272

Last Updated: 2020-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-08-16

Study Completion Date

2020-02-29

Brief Summary

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A prospective randomized controlled study was undertaken to compare the postoperative analgesic effect between ultrasound-guided serratus anterior plane block and intercostal nerve block after video-assisted thoracoscopic lobectomy.

Detailed Description

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Post-thoracotomy pain is one of the most notorious postsurgical pains that one can experience. The pain is known to last for an extensive period of time with significantly high intensity.

In field of thoracic surgery, video-assisted thoracoscopic surgery has been played an important role in alleviating the postoperative pain. In field of anesthesiology, various attempts to alleviate post-thoracotomy pain have been tried along advancement of thoracic surgical techniques. It began with postoperative medication of non-steroid anti-inflammatory drugs, opioids and progressed into implementations such as local analgesia, thoracic epidural block, paravertebral block, intercostal nerve block, interpleural block and serratus anterior plane block.

Many analgesic methods have been applied to alleviate postoperative pain in patients who have undergone thoracoscopic surgeries. However, there are no prospective randomized controlled studies between intercostal nerve block and serratus anterior plane block in video-assisted thoracoscopic lobectomy. The main purpose of this study is to compare and analyze the effects between conventional intercostal nerve block and newly introduced serratus anterior plane block in lung cancer patients who have undergone video-assisted thoracoscopic lobectomy.

This prospective study will discover the efficacy and differences between two methods.

Conditions

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Analgesia Postoperative Pain Lung Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Serratus Anterior Plane Block

Serratus Anterior Plane Block was performed just before the start of surgery after anesthetic induction through ultrasound-guidance. 20ml of 0.375% ropivacaine was slowly injected between the fascia of serratus anterior and latissimus dorsi near 5th rib.

Group Type EXPERIMENTAL

Thoracoscopic lobectomy

Intervention Type PROCEDURE

Thoracoscopic lobectomy was performed for lung cancer

Intercostal Nerve Block

Intercostal Nerve Block was performed just before closing the surgical incision while looking directly at the affected intercostal space. 10ml of 0.375% ropivacaine was delivered evenly at anterior and posterior intercostal spaces from the port site.

Group Type ACTIVE_COMPARATOR

Thoracoscopic lobectomy

Intervention Type PROCEDURE

Thoracoscopic lobectomy was performed for lung cancer

Interventions

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Thoracoscopic lobectomy

Thoracoscopic lobectomy was performed for lung cancer

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* lung cancer
* American Society of Anesthesiologists (ASA) I-III class
* Video-assisted thoracoscopic lobectomy

Exclusion Criteria

* previous history of allergy to local anesthetics
* psychological disorder
* chronic analgesics or sedatives use
* coagulopathy
* The presence of systemic infection or local infection at injection site
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kyungpook National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Saeyoung Kim, MD, PhD

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Saeyoung Kim

Role: PRINCIPAL_INVESTIGATOR

Kyungpook National University Hospital

Locations

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Kyungpook national university hospital

Daegu, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Jimin Heo

Role: CONTACT

Phone: +82-53-420-5430

Email: [email protected]

Saeyoung Kim

Role: CONTACT

Phone: +82-53-420-5873

Email: [email protected]

Facility Contacts

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Jimin Heo

Role: primary

Other Identifiers

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2019-07-008-002

Identifier Type: -

Identifier Source: org_study_id