Concussion Active Rehabilitation

NCT ID: NCT04248218

Last Updated: 2022-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

55 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-08-12

Study Completion Date

2022-06-30

Brief Summary

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In this study, the investigator plans a randomized trial of active rehabilitation and standard care for acute concussion management. The investigator hypothesizes that patients with acute concussions managed with active rehabilitation will have decreased risk of prolonged concussion symptoms.

Detailed Description

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Specific Aims:

To compare the risk of prolonged concussion symptoms (PCS) between an active rehabilitation and a standard care cohort after an acute concussion.

To determine if active rehabilitation compared to routine care reduces the risk of PCS for high-risk patients.

This is a prospective randomized control trial of pediatric patients in the emergency department (ED) diagnosed with an acute concussion. Patients 8-18 years old with an acute concussion diagnosis will be eligible. All patients will receive pedometers to monitor their activity levels. If the patient is in the control group the patient will receive standard concussion management per the treating ED physician. Patients in the active rehabilitation group will receive instructions based on the latest CDC concussion management guidelines that specify a symptom-limited progressive return to full activities. This group will be instructed to take at least 10,000 steps a day for five days on their pedometers.

One to five days after the ED concussion diagnosis a trained research coordinator will call all subjects to reinforce the management plan.

28 to 32 days post ED concussion diagnosis, research assistants will contact subjects via email or phone call to complete the concussion symptoms inventory.

Conditions

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Pediatric ALL Concussion, Mild Concussion, Brain Concussion, Intermediate

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a prospective randomized control trial of pediatric patients in the emergency department (ED) diagnosed with an acute concussion.

The randomization plan will include randomization based on sex.

Group A: active care Group B: routine/standard care
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Normal/Control

Control Group/Standard Care

Group Type NO_INTERVENTION

No interventions assigned to this group

Active Rehabilitation Group/Case

Active Rehabilitation Cohort/Intervention

Group Type ACTIVE_COMPARATOR

Active Rehabilitation Group/Case

Intervention Type BEHAVIORAL

If the patient is in the active rehabilitation group, the patient will receive instructions based on the latest CDC concussion management guidelines that specify a symptom-limited progressive return to full activities. This group will be instructed to take at least 10,000 steps a day for five days on their pedometers. In addition, they will also watch a two-minute video by the PI and research team reinforcing the active rehabilitation instructions.

Interventions

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Active Rehabilitation Group/Case

If the patient is in the active rehabilitation group, the patient will receive instructions based on the latest CDC concussion management guidelines that specify a symptom-limited progressive return to full activities. This group will be instructed to take at least 10,000 steps a day for five days on their pedometers. In addition, they will also watch a two-minute video by the PI and research team reinforcing the active rehabilitation instructions.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patient diagnosed with an acute concussion within 48 hours
* Patient greater than 8 and less than 19 years old

Exclusion Criteria

* Major psychiatric diagnosis (bipolar disorder, major depression, does NOT include ADHD/ADD)
* Cognitive delay
* GCS \< 14
* positive findings on head CT
* Any patient with intracranial surgery, pathology or instrumentation (e.g. VP shunt, brain tumor etc)
Minimum Eligible Age

8 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Children's National Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Jeremy Root

Assistant Professor of Pediatrics and Emergency Medicine, George Washington Univ School of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Children's National Medical Center

Washington D.C., District of Columbia, United States

Site Status

Countries

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United States

Other Identifiers

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Pro0012220

Identifier Type: -

Identifier Source: org_study_id

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