Non-invasive Identification of Preoperative Anaemia

NCT ID: NCT04247178

Last Updated: 2020-11-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

166 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-31

Study Completion Date

2020-03-17

Brief Summary

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Approximately 20% of patients undergoing elective orthopaedic surgery are anaemic. When not identified and treated before surgery, this can lead to requiring blood transfusions, which brings additional expenses, time and inconvenience to the patient.It is recommended that preoperative assessment involves investigation and where possible, treatment of anaemia.

The timescale between assessment and surgery makes it difficult to comply with guidelines without postponing surgery.

This study will investigate adult patients scheduled for elective orthopaedic surgery, where a full blood count is to be taken as part of routine care. A paired non-invasive reading of their blood will be taken. It will be conducted at The Royal Infirmary, Edinburgh. This device is not in use within the department currently but has been given free of charge for the study. There are no restrictions placed on the device except that it is not accurate for measuring haemoglobin \<8g.dL. Participant care will only be determined by results from the laboratory assay as per routine care, not the noninvasive device.

The device is CE marked for haemoglobin determination. Masimo (manufacturer) have released results in the accuracy of their monitor but with very little other information, for example, study population or precision. This study aims to answer how accurate and precise non-invasive measurements are in patients scheduled for orthopaedic surgery (there are no studies with these results) and whether anaemia can be identified earlier in the patient pathway i.e. an anaemia screen at time of surgical listing, therefore leaving ample time for treatment and optimisation of care.

The data from the study will not be shared with Masimo. There is ongoing work towards introducing and piloting a new pre-operative triage system where optimisable conditions e.g. anaemia are identified at the time of listing. This study would aid this work.

Detailed Description

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Conditions

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Anemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients undergoing elective orthopaedic surgery

No interventions assigned to this group

Healthy Volunteers

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* able to provide informed consent
* aged between 16-80 years old
* scheduled for elective orthopaedic surgery
* a full blood count (FBC) is to be taken as part of routine care


* able to provide informed consent
* aged between 16-80 years old

Exclusion Criteria

* Patients with haemoglobin disorders
* Raynaud's disease (or any other condition affecting the blood supply to the digits).


* Patients with haemoglobin disorders
* Raynaud's disease (or any other condition affecting the blood supply to the digits).
Minimum Eligible Age

16 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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NHS Lothian

OTHER_GOV

Sponsor Role collaborator

University of Edinburgh

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Royal Infirmary of Edinburgh

Edinburgh, The City of Edinburgh, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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AC19147

Identifier Type: -

Identifier Source: org_study_id