Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
100 participants
OBSERVATIONAL
2019-03-01
2019-11-01
Brief Summary
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Investigators perform a retrospective, single-center study in 2019. Patients were divided into two groups: OFA (with dexmedetomidine) or OBA (sufentanyl).
Investigators analyse the total postoperative opioid consumption in the 48 h after surgery. Investigators asses pain intensity in the 48 h after surgery, operative hemodynamic stability, Post-Operative Pain (POP) in Post-Anesthesia Care Unit (PACU) and POP on day 30.
All data are available in the medical record
Hypothesis: OFA can reduce post-operative opioids consumption, pain in lobectomy by video-assisted thoracoscopy surgery (VATS).
Detailed Description
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Conditions
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Keywords
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Group opioid free anesthesia
Patient benefit of the opioid free anesthesia protocol
Post-operative care
Retrospective collection of clinical data recorded in the electronic medical record.
The following variables were continuously recorded in the institutional database: age, gender, body weight, height, personal medical history, American Society of Anesthesiologists (ASA) score, type of thoracic surgery, the duration of surgery, duration of anesthesia (from intubation to extubation), the duration of PACU stay, the need for morphine titration, epinephrine, norepinephrine.
For data at day 30, the vast majority of patients were included in the enhanced recovery program and as such benefited from a consultation at 1 month with a coordination nurse who collected data on post-operative pain in a standardized manner.
All data was extracted from investigators institutional database and collected by a physician who was not involved in the care of the study patients.
Group opioid based anesthesia
Patient don't benefit of the opioid free anesthesia protocol
Post-operative care
Retrospective collection of clinical data recorded in the electronic medical record.
The following variables were continuously recorded in the institutional database: age, gender, body weight, height, personal medical history, American Society of Anesthesiologists (ASA) score, type of thoracic surgery, the duration of surgery, duration of anesthesia (from intubation to extubation), the duration of PACU stay, the need for morphine titration, epinephrine, norepinephrine.
For data at day 30, the vast majority of patients were included in the enhanced recovery program and as such benefited from a consultation at 1 month with a coordination nurse who collected data on post-operative pain in a standardized manner.
All data was extracted from investigators institutional database and collected by a physician who was not involved in the care of the study patients.
Interventions
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Post-operative care
Retrospective collection of clinical data recorded in the electronic medical record.
The following variables were continuously recorded in the institutional database: age, gender, body weight, height, personal medical history, American Society of Anesthesiologists (ASA) score, type of thoracic surgery, the duration of surgery, duration of anesthesia (from intubation to extubation), the duration of PACU stay, the need for morphine titration, epinephrine, norepinephrine.
For data at day 30, the vast majority of patients were included in the enhanced recovery program and as such benefited from a consultation at 1 month with a coordination nurse who collected data on post-operative pain in a standardized manner.
All data was extracted from investigators institutional database and collected by a physician who was not involved in the care of the study patients.
Eligibility Criteria
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Inclusion Criteria
* Opioid Free Anesthesia (OFA) administration was left to the discretion of the attending anesthetist according to his or her practices and habits.
* age 18 or over
* lobectomy or wedge resection by Video-Assisted Thoracoscopy Surgery (VATS)
Exclusion Criteria
* epidural analgesia use,
* thoracotomy conversion
* Patient-Controlled Analgesia with morphine (PCA)
* Patient who object to take part of the study.
18 Years
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Responsible Party
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Locations
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Department of Anesthesiology and Intensive Care - Louis Pradel University Hospital - Hospices Civils, Lyon, France
Bron, , France
Countries
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Other Identifiers
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VATOFA
Identifier Type: -
Identifier Source: org_study_id