Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
22 participants
INTERVENTIONAL
2021-04-28
2024-09-15
Brief Summary
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Detailed Description
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The current project will investigate the efficacy of two experimental cognitive training interventions in a sample of inpatients in treatment for AUD. While the effectiveness of CT to enhance function is supported by diverse literatures, it remains largely unexamined in AUD. The current project will interrogate the degree to which cognitive training interventions can "transfer" cognitive gains to untrained tasks/domains, and improve overall executive functioning. It will apply conceptual models from the CT and alcohol literatures to identify factors associated with CT efficacy. The impact of cognitive training on functional outcomes, including post-discharge drinking, will be investigated. Finally, relationships between cognitive recovery during treatment and post-discharge adaptation will be examined. Thus, the current work will be of substantial import to public health, alcohol science, and will inform future intervention efforts.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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Working Memory Training (WM)
Participants complete training in a working memory task designed to utilize individually-adapted difficulty levels.
Working Memory Training
Participants complete up to 12 sessions of computerized training (30-45 min each) in a working memory task designed to utilize individually-adapted difficulty levels.
Inhibitory Control Training (IC)
Participants complete training in an inhibitory control task designed to utilize individually-adapted difficulty levels.
Inhibitory Control Training
Participants complete up to 12 sessions of computerized training (30-45 min each) in an inhibitory control task designed to utilize individually-adapted difficulty levels.
Bias Modification Training (BM)
Participants complete training in an active comparator task designed to weaken approach responses to alcohol-associated cues.
Bias Modification Training
Participants complete up to 12 sessions of computerized training (30-45 min each) in a bias modification task designed to utilize individually-adapted difficulty levels.
Non-Trained control (NTC)
No active intervention is delivered beyond typical care.
No interventions assigned to this group
Interventions
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Working Memory Training
Participants complete up to 12 sessions of computerized training (30-45 min each) in a working memory task designed to utilize individually-adapted difficulty levels.
Inhibitory Control Training
Participants complete up to 12 sessions of computerized training (30-45 min each) in an inhibitory control task designed to utilize individually-adapted difficulty levels.
Bias Modification Training
Participants complete up to 12 sessions of computerized training (30-45 min each) in a bias modification task designed to utilize individually-adapted difficulty levels.
Eligibility Criteria
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Inclusion Criteria
* Meet DSM-5 criteria for alcohol use disorder
Exclusion Criteria
* Meet DSM-5 criteria for current/unremitted psychotic, panic, or bipolar disorders
25 Years
64 Years
ALL
No
Sponsors
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National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
University of Florida
OTHER
Responsible Party
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Principal Investigators
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Ben Lewis, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Florida
Locations
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University of Florida
Gainesville, Florida, United States
Countries
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Other Identifiers
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IRB201901330
Identifier Type: -
Identifier Source: org_study_id