Impact of AMATEA™️ on Physiological Measures and Gaming Performance in Active Gamers: a Placebo Controlled, Double-blind, Randomized Study

NCT ID: NCT04234529

Last Updated: 2021-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

59 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-01

Study Completion Date

2021-06-11

Brief Summary

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AMATEA™ is a patented dietary supplement consisting of a unique blend of caffeine and polyphenol antioxidants; standardized at 20% caffeine, 30% chlorogenic acids (similar to green coffee). In-house evaluations and anecdotal findings related to AMATEA have noted sustained energy without the typical "crash" and/or "jitters" experienced by some with caffeine ingestion alone.

The aim of the present study is to compare the effects of AMATEA and caffeine alone on various measures of cognitive performance, mood, and gaming performance in men and women who regularly engage in gaming activity. The investigators hypothesize that both AMATEA and caffeine will improve outcome measures more than placebo, with greater improvement noted for the AMATEA condition due to the addition of the chlorogenic acid.

Detailed Description

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The activity of "gaming" is increasing in popularity each year, with millions of young adults engaged in regular play. This has fueled the rise in nutrition and dietary supplementation strategies to aid gaming performance. Since caffeine has been widely used for purposes of improving athletic performance with both relatively low and high dosages, and more recently as a potential aid for "mind" games such as chess at a dosage of 400mg, this has been the nutrient of focus for many gamers. Other multi-component products are making their way to the market.

Active gamers claim to ingest such products regularly throughout their gameplay, which can span from 4-12 hours per session for regular gamers. AMATEA™ is a patented dietary supplement consisting of a unique blend of caffeine and polyphenol antioxidants; standardized at 20% caffeine, 30% chlorogenic acids (similar to green coffee). The product is also Generally Recognized as Safe (GRAS) and USDA organic.

While caffeine has been well-investigated for its performance boosting effects, chlorogenic acid has been reported to offer many potential health benefits. Specifically, it has been reported to improve select cognitive measures following regular intake, which may translate into more efficient performance with complex tasks-such as those involved with gaming.

In-house evaluations and anecdotal findings related to AMATEA have noted sustained energy without the typical "crash" and/or "jitters" experienced by some with caffeine ingestion alone. While caffeine can prove beneficial to many, some users experience "crashing" 2-3 hours post ingestion, while others feel too "wired" following use and may experience difficulty concentrating. AMATEA contains a relatively low concentration of caffeine per capsule (150mg) in an attempt to avoid such problems, while also containing chlorogenic acid. This may aid gamers who need to maintain fine motor skills and those who need to concentrate on complex activities for several hours continuously.

The aim of the present study is to compare the effects of AMATEA and caffeine alone on various measures of cognitive performance, mood, and gaming performance in men and women who regularly engage in gaming activity. The investigators hypothesize that both AMATEA and caffeine will improve outcome measures more than placebo, with greater improvement noted for the AMATEA condition due to the addition of the chlorogenic acid.

Conditions

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Healthy

Keywords

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AMATEA video games gaming energy supplement

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Participants will receive each of the 3 interventions over a 3 week period i.e. one acute dose once per week. The 3 interventions include 1) AMATEA, 2) Caffeine, or 3) Placebo
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators
Double-blinded

Study Groups

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AMATEA

3x 450mg capsules of AMATEA which contains 270mg of caffeine total

Group Type ACTIVE_COMPARATOR

AMATEA™

Intervention Type DIETARY_SUPPLEMENT

AMATEA™ is a patented dietary supplement consisting of a unique blend of caffeine and polyphenol antioxidants; standardized at 20% caffeine, 30% chlorogenic acids (similar to green coffee).

Total of 1.35g of AMATEA containing 270mg of caffeine.

Caffeine

3x 450mg capsules each containing 360mg of microcellulose and 90mg of caffeine (270mg caffeine total)

Group Type ACTIVE_COMPARATOR

Caffeine

Intervention Type DIETARY_SUPPLEMENT

1.08g of microcellulose and 270mg of caffeine.

Placebo

3x 450mg capsules of microcellulose

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

1.35g of microcellulose

Interventions

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AMATEA™

AMATEA™ is a patented dietary supplement consisting of a unique blend of caffeine and polyphenol antioxidants; standardized at 20% caffeine, 30% chlorogenic acids (similar to green coffee).

Total of 1.35g of AMATEA containing 270mg of caffeine.

Intervention Type DIETARY_SUPPLEMENT

Caffeine

1.08g of microcellulose and 270mg of caffeine.

Intervention Type DIETARY_SUPPLEMENT

Placebo

1.35g of microcellulose

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age 18-40 years
* male or female
* body mass index (BMI) between 18-34.9 kg/m2
* not be using tobacco products
* no diagnosed history of diabetes
* no diagnosed history of cardiovascular disease
* no diagnosed history of neurological disease
* no consumption of alcohol within 48 hours of testing
* consume \< 400mg caffeine daily
* no consumption of caffeine-containing beverages within at least 48 hours of testing
* blood metabolic parameters within normal limits
* if female, not be pregnant
* active gamers: playing at least 4 days per week, for at least 4 hours per day, for the past 12 months
* regularly playing the game Fortnite, for the past 3 months
* willing to play on our console systems and use their personal headset

Exclusion Criteria

* individuals younger than 18 years or greater than 40 years
* individuals weighing less than 115 pounds
* individuals with a BMI less than 18kg/m2 or greater than 35kg/m2
* individuals with a diagnosed history of diabetes, cardiovascular disease, or neurological disease
* individuals that consume greater than 400mg caffeine daily
* pregnant females
* non-active gamers
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Applied Food Sciences, Inc.

UNKNOWN

Sponsor Role collaborator

University of Memphis

OTHER

Sponsor Role lead

Responsible Party

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Richard Bloomer

Dean of School of Health Studies

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Richard Bloomer, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Memphis

Locations

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Center for Nutraceutical and Dietary Supplement Research

Memphis, Tennessee, United States

Site Status

Countries

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United States

Other Identifiers

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PRO-FY2020-65

Identifier Type: -

Identifier Source: org_study_id