Effects of Smartphone-based Treatment for Bipolar Disorder - the Smart Bipolar

NCT ID: NCT04230421

Last Updated: 2023-06-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-01

Study Completion Date

2026-07-01

Brief Summary

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The Smart Bipolar RCT is a pragmatic RCT aiming to investigate effects of smartphone-based add on treatment in large scale clinical practice (N= 200 patients).

Detailed Description

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Bipolar disorder is a complex illness with a complex treatment that differs during manic, depressed, and remitted states, frequently leaving patients with decreased quality of life and impaired psychosocial function. IT solutions have during recent years emerged as a possible way to optimize treatment, but the effects of digital health interventions are rarely investigated scientifically in health care services.

This is an application from the entire Mental Health Services, Capital Region of Denmark including all psychiatric centers in the region. The Smart Bipolar randomized controlled trial is a pragmatic trial aiming to investigate the effects of smartphone-based add-on treatment in large-scale clinical practice (N= 200 patients). Findings from the study will have a great impact on future IT monitoring and treatment in bipolar disorder.

Conditions

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Bipolar Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Monsenso with feedback

Daily smartphone-based monitoring and treatment using the Monsenso system with a clinical feedback loop feedback.

Group Type EXPERIMENTAL

The Monsenso system with feedback

Intervention Type DEVICE

See description under intervention

Monsenso without feedback

Daily smartphone-based monitoring and treatment using the Monsenso system WITHOUT a clinical feedback loop feedback.

Group Type ACTIVE_COMPARATOR

The Monsenso system without feedback

Intervention Type DEVICE

See description under intervention

Control

CAG Bipolar treatment alone and daily mood monitoring using only the mood monitoring part of the Monsenso system.

Group Type ACTIVE_COMPARATOR

CAG Bipola and mood monitoring only

Intervention Type DEVICE

See description under intervention

Interventions

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The Monsenso system with feedback

See description under intervention

Intervention Type DEVICE

The Monsenso system without feedback

See description under intervention

Intervention Type DEVICE

CAG Bipola and mood monitoring only

See description under intervention

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* All patients in CAG Bipolar, i.e., with a main diagnosis of bipolar disorder in the five large centers, in the Mental Health Services, Capital Region of Denmark (Psychiatric Center Copenhagen, Psychiatric Center Hilleroed, Psychiatric Center Amager, Psychiatric Center Glostrup and Psychiatric Center Ballerup)

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Maria Faurholt-Jepsen, MD, DMSc

UNKNOWN

Sponsor Role collaborator

The Mental Health Services in the Capital Region of Denmark

UNKNOWN

Sponsor Role collaborator

Mental Health Services in the Capital Region, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Lars Vedel Kessing

Prof., Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Psychiatric Center Copenhagen, Rigshospitalet

Copenhagen, , Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Lars Vedel Kessing, Prof., MD, DMSc

Role: CONTACT

+4538647073

Maria Faurholt-Jepsen, MD, DMSc

Role: CONTACT

+4538647073

Facility Contacts

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Maria Faurholt-Jepsen

Role: primary

Lars Vedel Kessing

Role: backup

References

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Faurholt-Jepsen M, Kyster NB, Dyreholt MS, Christensen EM, Bondo-Kozuch P, Lerche AS, Smidt B, Knorr U, Brondmark K, Cardoso AB, Mathiesen A, Sjaelland R, Norbak-Emig H, Sponsor LL, Mardosas D, Sarauw-Nielsen IP, Bukh JD, Heller TV, Frost M, Iversen N, Bardram JE, Busk J, Vinberg M, Kessing LV. The effect of smartphone-based monitoring and treatment including clinical feedback versus smartphone-based monitoring without clinical feedback in bipolar disorder: the SmartBipolar trial-a study protocol for a randomized controlled parallel-group trial. Trials. 2023 Sep 12;24(1):583. doi: 10.1186/s13063-023-07625-1.

Reference Type DERIVED
PMID: 37700334 (View on PubMed)

Other Identifiers

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H-19067259

Identifier Type: -

Identifier Source: org_study_id

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