Prospective Screening Programme for Malignant Tumors

NCT ID: NCT04230200

Last Updated: 2020-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-03-28

Study Completion Date

2020-03-30

Brief Summary

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In prospective part of study, the investigators have found that the parameters of routine blood tests can differentiate varieties of malignancy from healthy people.

The investigators enrolled healthy subjects and patients with malignancy that aged from 18 to 85,and collected their clinical data and blood tests result to build the model.And retrospectlly enroll healthy subjects and patients to test the model.

Detailed Description

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Conditions

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Hematologic Tests Malignant Tumor

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Healthy cohort

People who received routine physical examination including blood test, and after 3 year follow-up, have not been diagnosed as any kind of malignant tumor.

No interventions assigned to this group

Malignancy Cohort

People who were diagnosed as one of the following malignant disease: breast cancer, lung cancer, gastric cancer, esophageal cancer,colorectal cancer,nasopharyngeal cancer,liver cancer and cervical cancer

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Asymptomatic persons between the ages of 18 to 80 years
2. Chinese ethnicity
3. After 3 year follow-up, diagnosed with no malignant disease
4. Subject underwent routine blood tests in our center


1. diagnosis with the following malignant disease,breast cancer, lung cancer, gastric cancer, esophageal cancer,colorectal cancer,nasopharyngeal cancer,liver cancer and cervical cancer
2. Subject underwent routine blood tests in our center

Exclusion Criteria

1.With a history of malignant disease

For the cohort of patients with malignancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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First Affiliated Hospital, Sun Yat-Sen University

OTHER

Sponsor Role collaborator

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

Sponsor Role collaborator

Sun Yat-sen University

OTHER

Sponsor Role lead

Responsible Party

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Ruihua Xu

President

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ruihua Xu, Doctor

Role: PRINCIPAL_INVESTIGATOR

Sun Yat-sen University

Locations

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Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

Site Status

Countries

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China

References

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Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015 Mar;65(2):87-108. doi: 10.3322/caac.21262. Epub 2015 Feb 4.

Reference Type BACKGROUND
PMID: 25651787 (View on PubMed)

Heimbach JK, Kulik LM, Finn RS, Sirlin CB, Abecassis MM, Roberts LR, Zhu AX, Murad MH, Marrero JA. AASLD guidelines for the treatment of hepatocellular carcinoma. Hepatology. 2018 Jan;67(1):358-380. doi: 10.1002/hep.29086. No abstract available.

Reference Type BACKGROUND
PMID: 28130846 (View on PubMed)

Chan KCA, Woo JKS, King A, Zee BCY, Lam WKJ, Chan SL, Chu SWI, Mak C, Tse IOL, Leung SYM, Chan G, Hui EP, Ma BBY, Chiu RWK, Leung SF, van Hasselt AC, Chan ATC, Lo YMD. Analysis of Plasma Epstein-Barr Virus DNA to Screen for Nasopharyngeal Cancer. N Engl J Med. 2017 Aug 10;377(6):513-522. doi: 10.1056/NEJMoa1701717.

Reference Type BACKGROUND
PMID: 28792880 (View on PubMed)

Other Identifiers

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SCREEN-Pan Cancer

Identifier Type: -

Identifier Source: org_study_id

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