Vestibular Nerve Stimulation to Improve Sleep

NCT ID: NCT04219566

Last Updated: 2022-10-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-03-01

Study Completion Date

2022-07-31

Brief Summary

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A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings

The purpose of this investigation device study is to collect data that will be used to design appropriate pivotal studies that can be used for regulatory submissions, primarily in the United States of America (USA), but it may also be used to support submissions in other regions, including the European Union (EU).

Detailed Description

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Conditions

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Insomnia Sleep Sleep Disorders, Circadian Rhythm

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
Double Blind (Subject, Nursing staff, Co-coordinators, Outcomes Assessor and any other study staff who have contact with the subject)

Study Groups

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Active VeNS

The VeSTAL device will be placed on the head in a manner analogous to headphones and will deliver a small electrical current to the skin behind the ears, over the mastoid processes. Participants will be advised to use the device at home for 1 hour per day in the period immediately prior to sleep onset.

Group Type ACTIVE_COMPARATOR

VeNS

Intervention Type DEVICE

Non-invasive electrical vestibular nerve stimulation

Sham VeNS

The sham device looks identical to the active device and interacts with the app in a similar manner to the active device. However, it does not deliver vestibular stimulation to users. device will be placed on the head in a manner analogous to headphones and will deliver a small electrical current to the skin behind the ears, over the mastoid processes. Participants will be advised to use the device at home for 1 hour per day in the period immediately prior to sleep onset.

Group Type SHAM_COMPARATOR

Placebo device

Intervention Type DEVICE

Sham non-invasive electrical vestibular nerve stimulation

Interventions

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VeNS

Non-invasive electrical vestibular nerve stimulation

Intervention Type DEVICE

Placebo device

Sham non-invasive electrical vestibular nerve stimulation

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adults
* Both genders
* Ages 18-24 years inclusive
* Score above 14 in the insomnia severity index questionnaire
* Willingness to participate in the study.

Exclusion Criteria

* Use sleep medication
* Ear problems
* Under any kind of treatment
* Practicing sleep improving techniques
* Any other significant health-related problems.
Minimum Eligible Age

18 Years

Maximum Eligible Age

24 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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RD Gardi Medical College

UNKNOWN

Sponsor Role collaborator

Compliance Solutions Ltd.

INDUSTRY

Sponsor Role collaborator

Neurovalens Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sai Sailesh

Role: PRINCIPAL_INVESTIGATOR

RD Gardi Medical College

Locations

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RD Gardi Medical College

Ujjain, Madhya Pradesh, India

Site Status

Countries

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India

Other Identifiers

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IVS001S

Identifier Type: -

Identifier Source: org_study_id

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