PLASMA Mexico (PLASMA Mexico)

NCT ID: NCT04214899

Last Updated: 2024-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

254 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-30

Study Completion Date

2024-11-25

Brief Summary

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Collect data on Mexican patients diagnosed with Heart Failure with reduced ejection fraction, their treatments, and their progress in a real-world environment. Additional objectives will be analyzed, such as mortality, the use of resources associated with the follow-up of this group of patients and the barriers, if any, to receiving the indicated treatment.

Detailed Description

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* Identify the main epidemiological and clinical characteristics of patients with Heart Failure with reduced ejection fraction, as well as the medical treatment models used.
* Determine the prescription rate of a cardiovascular pharmacological treatment and the prescription and implant rate of a cardiac medical device in patients with Heart Failure with reduced ejection fraction.
* Determine the mortality rate and its classification in patients with Heart Failure with reduced ejection fraction.
* Identify the barriers, if any, to prescribing and implanting a cardiac medical device in those patients with a Class I recommendation according to the ACC/AHA/HRS 2017 guidelines.
* Determine the population with a profile of 1.5 primary prevention of sudden cardiac death (patients with Heart Failure in primary prevention who have one or more of the following risk factors: syncope or pre-syncope; left ventricular ejection fraction less than 25%; presence of non-sustained ventricular tachycardia; more than 10 ventricular extrasystoles per hour observed in a 24-hour Holter).
* Collect data on the use of resources associated with the follow-up of patients diagnosed with Heart Failure with reduced ejection fraction during a period of 12 months to perform a secondary economic analysis.

Conditions

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Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Men and women ≥18 years
* Patients with Heart Failure with LVEF ≤ 45% will be included
* Patients must be willing to comply with the study requirements and complete the Informed Consent Form (defined as the legally valid and documented confirmation of a patient's voluntary agreement to participate in the clinical study)

Exclusion Criteria

* Patients without Heart Failure or with Heart Failure with LVEF \> 45%
* Patients unable of comply with the Clinical Investigation Plan
* Patients who are already enrolled or plan to participate in a concurrent clinical study of any medication and/or device at any time during the course of this clinical study without prior documented approval of the Medtronic Study Manager
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic Cardiac Rhythm and Heart Failure

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Claudio Muratore

Role: STUDY_CHAIR

Medtronic

Locations

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ICMI: Instituto Cardiovascular de Mínima Invasión

Jalisco, Jalisco, Mexico

Site Status

CITIC

Mexico City, Mexico City, Mexico

Site Status

CECLIQ: Centro de Estudios Clínicos de Querétaro

Querétaro City, Querétaro, Mexico

Site Status

Helimedica

Naucalpan, State of Mexico, Mexico

Site Status

Centro Medico ABC Santa Fe

Mexico City, , Mexico

Site Status

ISSSTE Hospital General Tacuba

Mexico City, , Mexico

Site Status

Instituto Nacional de Cardiologia

Mexico City, , Mexico

Site Status

Countries

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Mexico

Other Identifiers

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MDT19012

Identifier Type: -

Identifier Source: org_study_id