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Study of Microbiota in Longevity County, Yongfu

NCT ID: NCT04210934

Last Updated: 2019-12-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-05-22

Study Completion Date

2016-05-31

Brief Summary

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This study is an observational study designed to adopt a cross-sectional study design. In the context of China's longevity town (East Asian population), Yongfu, Guangxi, the background of non-medical care and antibiotic use was explored, and the intestinal microecological balance increased with age and natural health. Longevity relationship. This study was completed using a household survey. Through routine clinical examinations and analysis of biochemical laboratory indicators, at the same time, a questionnaire for ADL(activities of daily living), cognitive function, and related elderly information was carried out on the elderly to comprehensively provide health information for each elderly. Based on the remaining stool samples and serum samples, the second-generation sequencing technology and other omics-based technologies were explored. No additional collection of human specimens and information is involved.

In addition, this study also hopes to explore the transmission rules of age-related bacteria in long-lived families, and the relationship with health phenotypes such as blood sugar, blood lipids, and cognitive function. Potential impact. In summary, this study will provide data support for exploring the relationship between healthy longevity and intestinal microecological balance based on the characteristic population of the longevity hometown.

Detailed Description

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Conditions

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Aging Healthy Aging

Keywords

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Microbiota multi-omics

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Obtained informed consent signed by volunteer or guardian
* Local lived for more than 50 years

Exclusion Criteria

* Subjects being treated with antibiotic in 3 months
* People who cannot cooperate with completing the survey
* Severe gastrointestinal disorders
Minimum Eligible Age

22 Years

Maximum Eligible Age

111 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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BGI-Shenzhen

INDUSTRY

Sponsor Role collaborator

Beijing Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Liang Sun, PhD

Director of Department of Medical Genetics

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Liang Sun, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Beijing Hospital

Ze Yang, M.D.

Role: STUDY_DIRECTOR

Beijing Hospital

Other Identifiers

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20170307

Identifier Type: -

Identifier Source: org_study_id