Trial Outcomes & Findings for Clinical Investigation of the Vision-R800 Device. (NCT NCT04208750)

NCT ID: NCT04208750

Last Updated: 2022-03-14

Results Overview

Patient questions of refraction preference for quickness, efficiency, comfort, and stress

Recruitment status

COMPLETED

Study phase

PHASE4

Target enrollment

119 participants

Primary outcome timeframe

at Visit 5 (final visit), up to 5 weeks

Results posted on

2022-03-14

Participant Flow

Participant milestones

Participant milestones
Measure
R-Refraction Then S-Refraction
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
S-Refraction Then R-Refraction
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
Overall Study
STARTED
58
61
Overall Study
Visit 2
58
61
Overall Study
Visit 3
58
53
Overall Study
Visit 4
43
47
Overall Study
COMPLETED
42
46
Overall Study
NOT COMPLETED
16
15

Reasons for withdrawal

Reasons for withdrawal
Measure
R-Refraction Then S-Refraction
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
S-Refraction Then R-Refraction
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
Overall Study
Lost to Follow-up
16
15

Baseline Characteristics

Sub-populations of participants were assessed for this baseline measure (young adults and presbyopes).

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
R-Refraction Then S-Refraction
n=58 Participants
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
S-Refraction Then R-Refraction
n=61 Participants
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
Total
n=119 Participants
Total of all reporting groups
Race (NIH/OMB)
Asian
7 Participants
n=58 Participants
8 Participants
n=61 Participants
15 Participants
n=119 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=58 Participants
0 Participants
n=61 Participants
0 Participants
n=119 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=58 Participants
2 Participants
n=61 Participants
3 Participants
n=119 Participants
Race (NIH/OMB)
White
48 Participants
n=58 Participants
47 Participants
n=61 Participants
95 Participants
n=119 Participants
Race (NIH/OMB)
More than one race
2 Participants
n=58 Participants
4 Participants
n=61 Participants
6 Participants
n=119 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=58 Participants
0 Participants
n=61 Participants
0 Participants
n=119 Participants
Region of Enrollment
United States
58 participants
n=58 Participants
61 participants
n=61 Participants
119 participants
n=119 Participants
Subject Classification
Count : Young Adults
27 Participants
n=58 Participants
33 Participants
n=61 Participants
60 Participants
n=119 Participants
Subject Classification
Count : Presbyopes
31 Participants
n=58 Participants
28 Participants
n=61 Participants
59 Participants
n=119 Participants
Subject Classification: Mean Age
Young Adults
23.89 years
STANDARD_DEVIATION 7.27 • n=27 Participants • Sub-populations of participants were assessed for this baseline measure (young adults and presbyopes).
22.06 years
STANDARD_DEVIATION 5.52 • n=33 Participants • Sub-populations of participants were assessed for this baseline measure (young adults and presbyopes).
22.88 years
STANDARD_DEVIATION 6.38 • n=60 Participants • Sub-populations of participants were assessed for this baseline measure (young adults and presbyopes).
Subject Classification: Mean Age
Presbyopes
56.26 years
STANDARD_DEVIATION 6.07 • n=31 Participants • Sub-populations of participants were assessed for this baseline measure (young adults and presbyopes).
57.39 years
STANDARD_DEVIATION 7.06 • n=28 Participants • Sub-populations of participants were assessed for this baseline measure (young adults and presbyopes).
56.80 years
STANDARD_DEVIATION 6.52 • n=59 Participants • Sub-populations of participants were assessed for this baseline measure (young adults and presbyopes).
Age, Categorical
<=18 years
6 Participants
n=58 Participants
8 Participants
n=61 Participants
14 Participants
n=119 Participants
Age, Categorical
Between 18 and 65 years
49 Participants
n=58 Participants
49 Participants
n=61 Participants
98 Participants
n=119 Participants
Age, Categorical
>=65 years
3 Participants
n=58 Participants
4 Participants
n=61 Participants
7 Participants
n=119 Participants
Age, Continuous
41.19 years
STANDARD_DEVIATION 17.57 • n=58 Participants
38.28 years
STANDARD_DEVIATION 18.81 • n=61 Participants
39.77 years
STANDARD_DEVIATION 18.14 • n=119 Participants
Sex: Female, Male
Female
47 Participants
n=58 Participants
43 Participants
n=61 Participants
90 Participants
n=119 Participants
Sex: Female, Male
Male
11 Participants
n=58 Participants
18 Participants
n=61 Participants
29 Participants
n=119 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
5 Participants
n=58 Participants
1 Participants
n=61 Participants
6 Participants
n=119 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
52 Participants
n=58 Participants
60 Participants
n=61 Participants
112 Participants
n=119 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
1 Participants
n=58 Participants
0 Participants
n=61 Participants
1 Participants
n=119 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=58 Participants
0 Participants
n=61 Participants
0 Participants
n=119 Participants

PRIMARY outcome

Timeframe: at Visit 5 (final visit), up to 5 weeks

Patient questions of refraction preference for quickness, efficiency, comfort, and stress

Outcome measures

Outcome measures
Measure
R-Refraction Then S-Refraction
n=42 Participants
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
S-Refraction Then R-Refraction
n=46 Participants
Vision R-800 Phoropter: Refraction utilizing the Vision R-800 Phoropter with resulting glasses Standard Phoropter: Refraction utilizing the standard phoropter with resulting glasses
Subjective Questionnaire Response
Quickness · Prefer VR800
22 Participants
32 Participants
Subjective Questionnaire Response
Quickness · Prefer Standard
5 Participants
3 Participants
Subjective Questionnaire Response
Quickness · No Preference
15 Participants
11 Participants
Subjective Questionnaire Response
Efficiency · Prefer VR800
25 Participants
26 Participants
Subjective Questionnaire Response
Efficiency · Prefer Standard
4 Participants
4 Participants
Subjective Questionnaire Response
Efficiency · No Preference
13 Participants
16 Participants
Subjective Questionnaire Response
Comfort · Prefer VR800
26 Participants
21 Participants
Subjective Questionnaire Response
Comfort · Prefer Standard
5 Participants
6 Participants
Subjective Questionnaire Response
Comfort · No Preference
11 Participants
19 Participants
Subjective Questionnaire Response
Stress · Prefer VR800
16 Participants
19 Participants
Subjective Questionnaire Response
Stress · Prefer Standard
7 Participants
10 Participants
Subjective Questionnaire Response
Stress · No Preference
19 Participants
17 Participants

Adverse Events

R-Refraction

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

S-Refraction

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Dawn Meyer

Indiana University

Phone: 812-855-0559

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place