Optimization of Sampling and Processing of Samples for Molecular Microbial Research on Ocular Surface Samples
NCT ID: NCT04193774
Last Updated: 2022-07-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
24 participants
INTERVENTIONAL
2019-08-19
2021-12-31
Brief Summary
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Detailed Description
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Furthermore, the effect of different extraction protocols on sequencing results will be assessed by sampling different volunteers in both eyes on non consecutive days.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
DIAGNOSTIC
DOUBLE
Study Groups
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Drop of artificial tears
A drop op Thealoz duo
Conjunctival swab
Swab of the conjunctival fornices of both eyes
artificial tears
One drop of artificial tears in the other eye
Drop op anesthetic
A drop of oxybuprocaïne
Conjunctival swab
Swab of the conjunctival fornices of both eyes
Oxybuprocaine Hydrochloride 0.4% Eye Drops
One drop of topical anesthesia in one eye
Interventions
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Conjunctival swab
Swab of the conjunctival fornices of both eyes
Oxybuprocaine Hydrochloride 0.4% Eye Drops
One drop of topical anesthesia in one eye
artificial tears
One drop of artificial tears in the other eye
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Fluent in written and verbal Dutch
* Capable of giving informed consent
Exclusion Criteria
* Medication usage in one eye only
18 Years
ALL
Yes
Sponsors
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Universitaire Ziekenhuizen KU Leuven
OTHER
Responsible Party
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Principal Investigators
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Heleen Delbeke, MD
Role: PRINCIPAL_INVESTIGATOR
Universitaire Ziekenhuizen KU Leuven
Locations
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University Hospitals Leuven, Department of Ophthalmology
Leuven, , Belgium
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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S62672
Identifier Type: -
Identifier Source: org_study_id
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