Trial Outcomes & Findings for A Validation Study of the NightOwl PAT-based Home Sleep Apnea Test (NCT NCT04191668)

NCT ID: NCT04191668

Last Updated: 2021-03-30

Results Overview

The evaluation of the Pearson correlation between the apnea-hypopnea index (AHI) estimate obtained from the NightOwl and the AHI determined from the polysomnography (PSG); The AHI is defined as the number of apnea or hypopnea divided by the (estimated) total sleep time expressed in hours.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

106 participants

Primary outcome timeframe

Through study completion, an average of 1 month.

Results posted on

2021-03-30

Participant Flow

Participant milestones

Participant milestones
Measure
PSG and NightOwl
Default patient recruitment During the study, for each execution day, all patients that have been scheduled for a PSG will be presented with an informed consent. All recruited patients shall be a part of the study during which they wear the NightOwl Sensor while undergoing the PSG exam. NightOwl: The NightOwl is a finger-mounted home sleep apnea testing device
Overall Study
STARTED
106
Overall Study
COMPLETED
106
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

For one participant, gender data could not be retrieved.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
PSG and NightOwl
n=73 Participants
Default patient recruitment During the study, for each execution day, all patients that have been scheduled for a PSG will be presented with an informed consent. All recruited patients shall be a part of the study during which they wear the NightOwl Sensor while undergoing the PSG exam. NightOwl: The NightOwl is a finger-mounted home sleep apnea testing device
Age, Continuous
59 years
STANDARD_DEVIATION 15.3 • n=73 Participants
Sex: Female, Male
Female
42 Participants
n=72 Participants • For one participant, gender data could not be retrieved.
Sex: Female, Male
Male
30 Participants
n=72 Participants • For one participant, gender data could not be retrieved.
Ethnicity (NIH/OMB)
Hispanic or Latino
39 Participants
n=73 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
33 Participants
n=73 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
1 Participants
n=73 Participants
Race/Ethnicity, Customized
Race · Black
18 Participants
n=73 Participants
Race/Ethnicity, Customized
Race · White
54 Participants
n=73 Participants
Race/Ethnicity, Customized
Race · Not reported
1 Participants
n=73 Participants
Region of Enrollment
United States
73 participants
n=73 Participants
BMI
32.6 kg/m^2
STANDARD_DEVIATION 8.2 • n=73 Participants

PRIMARY outcome

Timeframe: Through study completion, an average of 1 month.

Population: The population comprised those participants for which technically adequate polysomnography and home sleep apnea test data could be acquired.

The evaluation of the Pearson correlation between the apnea-hypopnea index (AHI) estimate obtained from the NightOwl and the AHI determined from the polysomnography (PSG); The AHI is defined as the number of apnea or hypopnea divided by the (estimated) total sleep time expressed in hours.

Outcome measures

Outcome measures
Measure
PSG and NightOwl
n=73 Participants
Default patient recruitment During the study, for each execution day, all patients that have been scheduled for a PSG will be presented with an informed consent. All recruited patients shall be a part of the study during which they wear the NightOwl Sensor while undergoing the PSG exam. NightOwl: The NightOwl is a finger-mounted home sleep apnea testing device
Pearson Correlation Between the AHI
0.909 Correlation coefficient

PRIMARY outcome

Timeframe: Through study completion, an average of 1 month.

Population: The population comprised those participants for which technically adequate polysomnography and home sleep apnea test data could be acquired.

The evaluation of the Pearson correlation between the total sleep time (TST) estimate obtained from the NightOwl and the TST determined from the PSG;

Outcome measures

Outcome measures
Measure
PSG and NightOwl
n=73 Participants
Default patient recruitment During the study, for each execution day, all patients that have been scheduled for a PSG will be presented with an informed consent. All recruited patients shall be a part of the study during which they wear the NightOwl Sensor while undergoing the PSG exam. NightOwl: The NightOwl is a finger-mounted home sleep apnea testing device
Pearson Correlation Between the TST
0.610 Correlation coefficient

PRIMARY outcome

Timeframe: Through study completion, an average of 1 month.

Population: The population comprised those participants for which technically adequate polysomnography and home sleep apnea test data could be acquired.

The evaluation of the level agreement (classification accuracy) between patient categorization (into sleep apnea severity categories) obtained by the NightOwl and those obtained by the PSG. This measure is calculated by dividing the number of participants on which both NightOwl and the PSG agree on the sleep apnea severity category by the total number of participants.

Outcome measures

Outcome measures
Measure
PSG and NightOwl
n=73 Participants
Default patient recruitment During the study, for each execution day, all patients that have been scheduled for a PSG will be presented with an informed consent. All recruited patients shall be a part of the study during which they wear the NightOwl Sensor while undergoing the PSG exam. NightOwl: The NightOwl is a finger-mounted home sleep apnea testing device
The Evaluation of the Level of Agreement (Classification Accuracy) Between Patient Categorization
0.685 Ratio

Adverse Events

PSG and NightOwl

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Frederik Massie

Ectosense

Phone: +1 786 305 8547

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place