Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

253 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-01

Study Completion Date

2017-01-01

Brief Summary

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Liver transplantation is the definitive treatment in patients with chronic liver disease. Neurological complications (NC) occur commonly after liver transplantation. The investigators aim to evaluate the incidence, risk factors and predictors of neurological complications in both living donor and deceased donor transplantation done in the hospital. Between January 2011 to December 2016, 253 liver transplant recipients were recruited for this study. The investigators recorded the incidence of neurological complications, their median time of onset, their relationship with etiology of chronic liver disease, and the risk factors for the complications. The investigators also studied the relationship of neurological complications with duration of hospital and ICU stay, and survival. Using multivariate forward regression analysis , the investigators developed a scoring system for prediction of neurological complications in liver transplantation.

Detailed Description

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Conditions

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Liver Transplant; Complications Neurologic Complication Postoperative Complications

Keywords

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liver transplantation neurological complications postoperative complications

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients undergoing liver transplant surgery
* 18-65 years

Exclusion Criteria

* pregnant patients
* Acute Liver Failure, Acute on Chronic Liver Failure

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Karthik T Ponnappan, DM

Role: PRINCIPAL_INVESTIGATOR

ILBS

Other Identifiers

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ILBS - Liver Transplant-2

Identifier Type: -

Identifier Source: org_study_id