Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer
NCT ID: NCT04181463
Last Updated: 2025-10-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
PHASE2
112 participants
INTERVENTIONAL
2025-11-05
2025-12-30
Brief Summary
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Detailed Description
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Inhalation of the study solution may help to control your nausea. Future patients may benefit from what is learned. There may be no benefits for you in this study.
Your participation is completely voluntary. Before choosing to take part in this study, you should discuss with the study team any concerns you may have, including side effects, potential expenses, and time commitment.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Arm I (isopropyl alcohol)
Patients receive isopropyl alcohol via nasal inhalation.
Isopropyl Alcohol
Given via nasal inhalation
Questionnaire Administration
Ancillary studies
Arm II (placebo)
Patients receive placebo via nasal inhalation.
Placebo
Given via nasal inhalation
Questionnaire Administration
Ancillary studies
Interventions
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Isopropyl Alcohol
Given via nasal inhalation
Placebo
Given via nasal inhalation
Questionnaire Administration
Ancillary studies
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Diagnosis of cancer
* Able to read/write in English
* Referred to supportive care service as an inpatient or outpatient
* Rate anxiety as =\< 4 on ESAS-FS (Edmonton Symptom Assessment Scale-Financial Distress and Spiritual Pain)
* Participants must agree to inhale isopropyl alcohol
Exclusion Criteria
* Received medical procedures (e.g. blood draws) which required exposure of isopropyl alcohol in the last 30 minutes
* Inability to inhale through nares (including recent upper respiratory infection)
* Known allergy to isopropyl alcohol
* Delirium (i.e., score \>= 7 on the Memorial Delirium Assessment Scale \[MDAS\])
* Have never been on anti-emetics during the course of the treatment here (anti-emetic naive)
18 Years
ALL
No
Sponsors
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National Cancer Institute (NCI)
NIH
M.D. Anderson Cancer Center
OTHER
Responsible Party
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Principal Investigators
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Yvonne J Heung
Role: PRINCIPAL_INVESTIGATOR
M.D. Anderson Cancer Center
Locations
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M D Anderson Cancer Center
Houston, Texas, United States
Countries
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Central Contacts
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Facility Contacts
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Yvonne J. Heung
Role: primary
Related Links
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M D Anderson Cancer Center
Other Identifiers
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NCI-2019-07377
Identifier Type: REGISTRY
Identifier Source: secondary_id
2019-0472
Identifier Type: OTHER
Identifier Source: secondary_id
2019-0472
Identifier Type: -
Identifier Source: org_study_id
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