Environmental Risk Factors of Mesh Infection After Abdominal Wall Hernia Repair

NCT ID: NCT04174976

Last Updated: 2019-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-28

Study Completion Date

2022-01-01

Brief Summary

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Mesh infection is the main complication in abdominal hernia repair. In case of infection, a conservative management of mesh is not always possible. The removal of the mesh (occurring in 5.1% to 8% of wall hernia repair) increases the risk of recurrence and surgical morbidity.

Within our digestive surgery department (CHRU de Nancy), an infection rate of 10.7% (32 cases out of 298 patients with wall hernia repair) was observed between January 2016 and December 2018. This rate is higher than those usually described in the literature.

Several studies have identified predictors of mesh infection and explantation after abdominal wall hernia repair. The influence of the operating environment (temperature, hygrometry, pressure, number of people present, etc.) has, to our knowledge, never been studied.

If the risk of prosthesis infection is influenced by one or more of these extrinsic characteristics, it is possible to act on these practices to reduce this risk.

The main purpose of this study is to identify the characteristics specific to the intervention and the operating environment associated with mesh infection after abdominal wall hernia reconstruction

Detailed Description

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It's a prospective, mono-centric study carried out on a cohort of patients followed in the digestive surgery department of the CHRU of Nancy

All patients who underwent a wall hernia repair between 28/12/2017 and 28/12/2020 in the digestive and general surgery department of the CHU of Nancy were included.

During the operative time, the nurses have to fill a survey with characteristics specific to the intervention and the operating environment.

Patients in this study have been followed for at least one year at the Nancy CHRU in order to be aware of the occurence of mesh infection and surgery for mesh explantation.

Conditions

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Surgical Site Infection

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Wall hernia repair

All patients admitted for wall hernia repair with mesh between 28/12/2017 and 28/12/2020.

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wall hernia repair

Intervention Type PROCEDURE

Wall hernia repair with mesh

Interventions

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wall hernia repair

Wall hernia repair with mesh

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients admitted for wall hernia repair with mesh between 28/12/2017 and 28/12/2020

Exclusion Criteria

* Emergency surgery
* Laparoscopic
* Pregnancy
* Adults under legal guardianship
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Estelle Vigneron

Role: PRINCIPAL_INVESTIGATOR

CHU NANCY

Locations

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Estelle Vigneron

Nancy, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Estelle Vigneron

Role: CONTACT

Phone: 0619676726

Email: [email protected]

Facility Contacts

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Estelle Vigneron

Role: primary

Other Identifiers

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2019PI187

Identifier Type: -

Identifier Source: org_study_id