Evaluation of the Stiffness and Pressure Applied on the Lower Leg by a New Compression Bandage on Healthy Subjects

NCT ID: NCT04159844

Last Updated: 2019-11-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-09-03

Study Completion Date

2019-11-29

Brief Summary

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This study evaluates the stiffness and interface pressures of a new compression system URGOBD001 on healthy subjects, compares with a short stretch bandage and a multi component bandage.

Detailed Description

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Compression therapy is widely used in the treatment of chronic venous leg ulcers (VLUs). The clinical performance of a compression system depends on the apply pressure and the stiffness.

The static stiffness index (SSI) is defined by the difference in interface pressure measured when the subject is standing (working pressure) and the interface pressure measured when the subject is in the lying position (resting pressure).

Conditions

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Healthy Subjects

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

3 separate sets :

* URGOBD001 SSI compared with the SSI of a short stretch bandage
* URGOBD001 SSI associated with wading bandage compared with the SSI of a short stretch bandage
* URGOBD001 SSI compared with the SSI of a multi component bandage.
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Short stretch bandage

Application with 50% overlap in combinaison with wading

Group Type ACTIVE_COMPARATOR

URGOBD001

Intervention Type DEVICE

Application with 50% overlapping

Multi componant bandage

Application with 50% overlap

Group Type ACTIVE_COMPARATOR

URGOBD001

Intervention Type DEVICE

Application with 50% overlapping

Short stretch bandage bis

Application with 50% overlap in combinaison with wading

Group Type ACTIVE_COMPARATOR

URGOBD001 associated with wading

Intervention Type DEVICE

Application with 50% overlapping in association with wading

Interventions

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URGOBD001

Application with 50% overlapping

Intervention Type DEVICE

URGOBD001 associated with wading

Application with 50% overlapping in association with wading

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subject with a body mass index of less than 30 (BMI = kg / m²),
* Subject presenting a healthy skin on both legs without any sign of dermatological lesion,
* Subject presenting a venous doppler of the lower limbs without detectable anomaly
* Subject with a ankle brachial pressure index (ABPI) greater than 0.9 and less than 1.3 for each of the lower limbs,
* Subject accepting to wear a compressive system on both legs for a period of three days.

Exclusion Criteria

* Subject with chronic venous insufficiency whose stage is greater than or equal to 2 (CEAP classification of chronic venous diseases)
* Subject with type I or II diabetes
* Subject with lipoedema and / or dismorphic leg
* Subject presenting ankle ankylosis
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Laboratoires URGO

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Benigni JP, MD

Role: PRINCIPAL_INVESTIGATOR

Intertek France clinical studies

Locations

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Intertek France Clinical studies

Paris, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Batot Géraldine, PhD

Role: CONTACT

+33 3 80 44 28 46

Other Identifiers

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F-19-06-BD001

Identifier Type: -

Identifier Source: org_study_id

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