A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation
NCT ID: NCT04141449
Last Updated: 2025-12-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
PHASE2
874 participants
INTERVENTIONAL
2020-11-18
2026-09-30
Brief Summary
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Detailed Description
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The trial includes a community education component focused on cancer awareness and importance of early diagnosis and a patient navigation component that aims to expedite the diagnostic evaluation. Community education will be directed at approximately 50,000 community residents (30 years and older). We anticipate approximately 1500 cancer suspects will be identified by their clinic providers.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
NONE
Study Groups
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Potlako intervention
* Provider oncology training focused on detection of cancer symptoms/signs and performance of appropriate diagnostic evaluation
* Community-led cancer symptom awareness campaign to educate residents on methods and importance of early detection of cancer
* Support/counselling call after initial clinician recognition that patient requires evaluation for possible cancer.
* Cross-sectional community-facing activities partnered with longitudinal clinic-based targeted educational program
* Remote phone/SMS-based cancer suspect navigation program to support and expedite evaluation for symptoms/signs of possible cancer.
Potlako intervention
Combined provider, patient, and health system intervention to expedite cancer diagnosis and care.
Enhanced Care
* Provider oncology training focused on detection of cancer symptoms/signs and performance of appropriate diagnostic evaluation.
* Support/counselling call after initial clinician recognition that patient requires evaluation for possible cancer.
Enhanced care
Provider education and limited patient counseling.
Interventions
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Potlako intervention
Combined provider, patient, and health system intervention to expedite cancer diagnosis and care.
Enhanced care
Provider education and limited patient counseling.
Eligibility Criteria
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Inclusion Criteria
* Age 30 years or older
* engaged in longitudinal care for chronic health problem
* resident of study community
* Botswana citizen
* Age 30 years or older
* resident of study community
* Recorded as a cancer suspect by clinic staff
Exclusion Criteria
* Educational messaging could interfere with clinical management or increase distress in the opinion or clinic or research staff
2. Cancer suspects
* Involuntary incarceration
* Unable or unwilling to provide confirmation of informed consent
* Already engaged in oncology care
30 Years
ALL
Yes
Sponsors
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Botswana Harvard AIDS Institute Partnership
OTHER
Dana-Farber Cancer Institute
OTHER
National Cancer Institute (NCI)
NIH
Rutgers Cancer Institute of New Jersey
OTHER
Brigham and Women's Hospital
OTHER
Responsible Party
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Scott Lee Dryden-Peterson
Assistant Professor
Principal Investigators
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Scott Dryden-Peterson, MD, MSc
Role: PRINCIPAL_INVESTIGATOR
Brigham and Women's Hospital, Botswana Harvard AIDS Institute
Locations
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Botswana Harvard AIDS Institute
Gaborone, , Botswana
Countries
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Provided Documents
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Document Type: Informed Consent Form
Other Identifiers
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BHP0120
Identifier Type: -
Identifier Source: org_study_id