Trial Outcomes & Findings for Prevention of OUD: The HOME Project (Housing, Opportunities, Motivation and Engagement) (NCT NCT04135703)

NCT ID: NCT04135703

Last Updated: 2025-09-15

Results Overview

frequency (% days in prior 90) of opioid use is measured at baseline, 3, 6, 9 and 12 months post-baseline

Recruitment status

COMPLETED

Study phase

Target enrollment

240 participants

Primary outcome timeframe

12 months

Results posted on

2025-09-15

Participant Flow

394 youth approached, 240 eligible and enrolled.

Failed: (n=154) * Not homeless (n=20) * Over the age of 24 (n=2) * Under the age of 18 (n=7) * Met DSM 5 criteria for OUD (n=27) * Declined Participation (n=39) * Failed to return (n=43) * Refused to wear a mask during intake (n=1) * Unable to focus to complete intake (n=1) * Difficulty/unable to answer questions (n=5) * Could not show proof of Guardianship (n=2) * Had difficulty understanding the project/process (n=7)

Participant milestones

Participant milestones
Measure	Risk Prevention Services +Housing Opioid and related prevention services included Strengths-Based Outreach and Advocacy (SBOA), MI, HIV risk and suicide prevention (CTSP) as well as rental and utility assistance for 6 months.	Risk Prevention Services Only Opioid and related prevention services included Strengths-Based Outreach and Advocacy (SBOA), MI, HIV risk and suicide prevention (CTSP).
Overall Study STARTED	120	120
Overall Study COMPLETED	120	120
Overall Study NOT COMPLETED	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Prevention of OUD: The HOME Project (Housing, Opportunities, Motivation and Engagement)

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Risk Prevention Services +Housing n=120 Participants Opioid and related prevention services included Strengths-Based Outreach and Advocacy (SBOA), MI, HIV risk and suicide prevention (CTSP) as well as rental and utility assistance for 6 months.	Risk Prevention Services Only n=120 Participants Opioid and related prevention services included Strengths-Based Outreach and Advocacy (SBOA), MI, HIV risk and suicide prevention (CTSP).	Total n=240 Participants Total of all reporting groups
Age, Continuous	21.8 years STANDARD_DEVIATION 1.84 • n=5 Participants	20.93 years STANDARD_DEVIATION 1.82 • n=7 Participants	21.05 years STANDARD_DEVIATION 1.83 • n=5 Participants
Sex: Female, Male Female	64 Participants n=5 Participants	53 Participants n=7 Participants	117 Participants n=5 Participants
Sex: Female, Male Male	56 Participants n=5 Participants	67 Participants n=7 Participants	123 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	2 Participants n=5 Participants	0 Participants n=7 Participants	2 Participants n=5 Participants
Race (NIH/OMB) Asian	5 Participants n=5 Participants	2 Participants n=7 Participants	7 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	65 Participants n=5 Participants	72 Participants n=7 Participants	137 Participants n=5 Participants
Race (NIH/OMB) White	25 Participants n=5 Participants	30 Participants n=7 Participants	55 Participants n=5 Participants
Race (NIH/OMB) More than one race	21 Participants n=5 Participants	15 Participants n=7 Participants	36 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	2 Participants n=5 Participants	1 Participants n=7 Participants	3 Participants n=5 Participants
% days opioid use in prior 90 days	.35 % of days of opioid use in prior 90 days STANDARD_DEVIATION .30 • n=5 Participants	.32 % of days of opioid use in prior 90 days STANDARD_DEVIATION .25 • n=7 Participants	.335 % of days of opioid use in prior 90 days STANDARD_DEVIATION .275 • n=5 Participants

PRIMARY outcome

Timeframe: 12 months

Population: Frequency of opioid use in prior 90 days (percentage of days use) was assessed at each follow-up point (3, 6, 9 and 12-months post-baseline) using the Form 90 interview.

frequency (% days in prior 90) of opioid use is measured at baseline, 3, 6, 9 and 12 months post-baseline

Outcome measures

Outcome measures
Measure	Risk Prevention Services +Housing n=120 Participants Opioid and related prevention services included Strengths-Based Outreach and Advocacy (SBOA), MI, HIV risk and suicide prevention (CTSP) as well as rental and utility assistance for 6 months.	Risk Prevention Services Only n=120 Participants Opioid and related prevention services included Strengths-Based Outreach and Advocacy (SBOA), MI, HIV risk and suicide prevention (CTSP).
Frequency (% Days) of Opioid Use in Prior 3 Months	0 % days opioid use Standard Deviation 0	0 % days opioid use Standard Deviation 0

Adverse Events

Risk Prevention Services +Housing

Serious events: 0 serious events

Other events: 0 other events

Deaths: 4 deaths

Risk Prevention Services Only

Serious events: 0 serious events

Other events: 0 other events

Deaths: 1 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Natasha Slesnick

The Oho State University

Phone: 6142478469

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place