Versi Retriever Approving Trial in Japan

NCT ID: NCT04129203

Last Updated: 2020-11-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

58 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-01

Study Completion Date

2021-12-31

Brief Summary

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This is Versi Retriever mechanical thrombectomy device approving study in Japan. Multi center, single arm, prospective registry trial. Physicians control trial, conducted my N Sakai, Kobe City Medical Center General Hospital.

Detailed Description

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This is Versi Retriever mechanical thrombectomy device approving study in Japan. Multi center, single arm, prospective registry trial. Physicians control trial, conducted my N Sakai, Kobe City Medical Center General Hospital.

60 cases will be enrolled and 90 days follow up need. Primary endpoint is favorable clinical outcome, mRS 0-2. Secondary endpoint are mortality in 90days, immediate successful recanalization, TICI 2b-3, symptomatic intracranial hemorrhage, and any adverse event related to device and or procedure.

Conditions

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Stroke, Acute

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Trial arm

Mechanical thrombectomy using Versi Retriever

Group Type EXPERIMENTAL

Versi Retriever thrombectomy

Intervention Type DEVICE

Mechanical thrombectomy using Versi Retriever

Interventions

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Versi Retriever thrombectomy

Mechanical thrombectomy using Versi Retriever

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* acute onset neurological sympto m related to occluded vessel
* within 8 hours from onset to tre atment or within 24 hours from onset to treatment with imaging diagnosis
* contra-indication or failed to int ravenous rt-PA
* accessible occlusion at ICA, MC A, VA, BA, PCA
* 5-30 of NIHSS
* 0-2 of mRS before onset
* obtain documented informed co ntent

Exclusion Criteria

* following condition; arterial diss ection, engird, inaccessible turtuousity, difficult access by 50% or m ore stenosis, acute intracranial hemorrhage, space occuping lesion or brain tumor, major early ischemic change in brain
* occlude 2 major vessel territory
* allege for contrast media,
* abnormal PTT/APTT within 4 h ours intravenous heparin
* hemorrhagic tendency or 3 or more INR with Warfarin administration
* 30000cc or less of Platelet
* 50mg/dL or less of blood sugar
* uncontrolled blood pressure, 185mmHg or more at systolic, 110m mHg or more at diastolic
* 90days or less life expancy
* pregnant or lactating
* join another trial of medicine or medical device
* ineligible for trial
Minimum Eligible Age

20 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kobe City General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Nobuyuki Sakai

Director, Neurosurgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nobuyuki Sakai, MD DMSc

Role: STUDY_CHAIR

Kobe City Medical Center General Hospital

Locations

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Kobe City Medical Center General Hospital

Kobe, Hyōgo, Japan

Site Status RECRUITING

Countries

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Japan

Central Contacts

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Nobuyuki Sakai, MD DMSc

Role: CONTACT

81783024321 ext. 080

Chiaki Sakai, MD PhD

Role: CONTACT

81783024321

Facility Contacts

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Nobuyuki Sakai, MD, DMSc

Role: primary

81783024321 ext. 080

Chiaki Sakai, MD PhD

Role: backup

81783024321

Other Identifiers

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VS-01

Identifier Type: -

Identifier Source: org_study_id