Trial Outcomes & Findings for Shared Decision-Making: AFib 2gether Mobile App (NCT NCT04118270)

NCT ID: NCT04118270

Last Updated: 2022-05-02

Results Overview

Patients evaluated the perceived usefulness of the AFib 2gether mobile application by taking the Mobile App Rating Scale (MARS) questionnaire. This evaluated 3 domains: functionality, aesthetics, and a star-based question. These scores are rated 1-5 with 5 being the highest (best) score.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

50 participants

Primary outcome timeframe

Immediately after visit

Results posted on

2022-05-02

Participant Flow

We identified 40 patients seeing 13 cardiology providers. Of the 40 patients, 2 were later found ineligible and 1 patient was disenrolled due to provider preference leaving us with 37 patient encounters to analyze. Of the 13 providers, 10 completed the accuracy assessment.

Participant milestones

Participant milestones
Measure
AFib 2gether(TM) App
Patients with known Atrial Fibrillation will be assigned to download and use an app targeted at determining stroke risk and increasing knowledge of Atrial Fibrillation and stroke risk along with treatment options and will use this information to facilitate a discussion with their cardiovascular provider. Afib 2gether TM Mobile Application: The Afib 2gether mobile app determines a patient's stroke risk through a series of questions that the patient will answer in the app.
Providers
Providers caring for the patients with known Atrial Fibrillation will be asked to review the patients' stroke risk score on the AFib 2gether app and compare to their clinical assessment for accuracy.
Overall Study
STARTED
37
13
Overall Study
Completed Provider Accuracy Assessment
0
10
Overall Study
COMPLETED
37
13
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Shared Decision-Making: AFib 2gether Mobile App

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
AFib 2gether(TM) App
n=37 Participants
Patients with known Atrial Fibrillation will be assigned to download and use an app targeted at determining stroke risk and increasing knowledge of Atrial Fibrillation and stroke risk along with treatment options and will use this information to facilitate a discussion with their cardiovascular provider. Afib 2gether TM Mobile Application: The Afib 2gether mobile app determines a patient's stroke risk through a series of questions that the patient will answer in the app.
Providers
Providers caring for the patients with known Atrial Fibrillation will be asked to review the patients' stroke risk score on the AFib 2gether app and compare to their clinical assessment for accuracy. Baseline measures were not collected for providers.
Total
n=37 Participants
Total of all reporting groups
Age, Customized
Age: 75+
17 Participants
n=93 Participants
17 Participants
n=27 Participants
Age, Customized
Age: 65-74
14 Participants
n=93 Participants
14 Participants
n=27 Participants
Age, Customized
Age: <65
6 Participants
n=93 Participants
6 Participants
n=27 Participants
Sex: Female, Male
Female
11 Participants
n=93 Participants
11 Participants
n=27 Participants
Sex: Female, Male
Male
26 Participants
n=93 Participants
26 Participants
n=27 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=93 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Asian
0 Participants
n=93 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=93 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=93 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
White
36 Participants
n=93 Participants
36 Participants
n=27 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=93 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Unknown or Not Reported
1 Participants
n=93 Participants
1 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 2
9 Participants
n=93 Participants
9 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 3
10 Participants
n=93 Participants
10 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 4
9 Participants
n=93 Participants
9 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 5
6 Participants
n=93 Participants
6 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 6
2 Participants
n=93 Participants
2 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 7
0 Participants
n=93 Participants
0 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 8
0 Participants
n=93 Participants
0 Participants
n=27 Participants
Stroke Risk Score
CHA2DS2-VASc score: 9
1 Participants
n=93 Participants
1 Participants
n=27 Participants

PRIMARY outcome

Timeframe: Immediately after visit

Population: Patients with a stroke risk score of 2 or higher and have a diagnosis of AF.

Patients evaluated the perceived usefulness of the AFib 2gether mobile application by taking the Mobile App Rating Scale (MARS) questionnaire. This evaluated 3 domains: functionality, aesthetics, and a star-based question. These scores are rated 1-5 with 5 being the highest (best) score.

Outcome measures

Outcome measures
Measure
Patient
n=37 Participants
Patients with a stroke risk score of 2 or higher and have a active diagnosis of atrial fibrillation (AF).
Patient MARS Scores
Functionality
4.51 score on a scale
Standard Deviation 0.61
Patient MARS Scores
Aesthetics
4.26 score on a scale
Standard Deviation 0.51
Patient MARS Scores
Star-Based
4.24 score on a scale
Standard Deviation 0.89

SECONDARY outcome

Timeframe: Immediately after visit.

Population: Providers are considered to be enrolled in the study.

Providers were asked to navigate the app features and rate their overall opinion of the mobile app by answering questions using the Mobile App Rating Scale (MARS). This scale evaluates 3 domains: functionality, aesthetics, and a star-based rating question. These scores are rated 1-5 with 5 being the highest (best) score.

Outcome measures

Outcome measures
Measure
Patient
n=13 Participants
Patients with a stroke risk score of 2 or higher and have a active diagnosis of atrial fibrillation (AF).
Provider MARS Scores
Functionality
4.19 units on a scale
Standard Deviation 0.50
Provider MARS Scores
Aesthetics
4.04 units on a scale
Standard Deviation 0.50
Provider MARS Scores
Star-Based
3.76 units on a scale
Standard Deviation 0.44

SECONDARY outcome

Timeframe: Immediately after visit

This was an evaluation of why the patient was not on an anticoagulant (AC) prior to their appointment.

Outcome measures

Outcome measures
Measure
Patient
n=37 Participants
Patients with a stroke risk score of 2 or higher and have a active diagnosis of atrial fibrillation (AF).
Reason Why the Patient Was Not on AC Prior to Their Appointment
Low AF Burden
16 participants
Reason Why the Patient Was Not on AC Prior to Their Appointment
Refused
10 participants
Reason Why the Patient Was Not on AC Prior to Their Appointment
Not Listed
5 participants
Reason Why the Patient Was Not on AC Prior to Their Appointment
Fall Risk
1 participants
Reason Why the Patient Was Not on AC Prior to Their Appointment
GI Bleed
2 participants
Reason Why the Patient Was Not on AC Prior to Their Appointment
Other Bleed
3 participants

SECONDARY outcome

Timeframe: Immediately after visit.

Population: Providers are considered enrolled in the study.

The provider was asked to review the patients stroke risk score on the AFib 2gether app and compare to provider clinical assessment for accuracy. The number of accurate scores were recorded. Ten of the original thirteen providers completed this assessment.

Outcome measures

Outcome measures
Measure
Patient
n=10 Participants
Patients with a stroke risk score of 2 or higher and have a active diagnosis of atrial fibrillation (AF).
Afib 2gether Accuracy Assessment
10 accurate scores

OTHER_PRE_SPECIFIED outcome

Timeframe: up to 6 months

Population: Patients with AF with a stroke risk score that is 2 or higher.

This outcome measures the number of patient participants with a CHA2DS2-VASc stroke scale score of 2 or higher who are placed on anticoagulation therapy following cardiology appointment. Patients switch to AC will be monitored via the electronic health record. The CHA2DS2-VASc scale is an evaluation of stroke risk for patients with atrial fibrillation. The scale is a composite of 7 questions, with an overall scale score of 0 to 9, with low scores indicating low risk for stroke, and high scores indicating high risk for stroke.

Outcome measures

Outcome measures
Measure
Patient
n=37 Participants
Patients with a stroke risk score of 2 or higher and have a active diagnosis of atrial fibrillation (AF).
Number of Patients Placed on Anticoagulation After Cardiology Appointment
12 Participants

Adverse Events

AFib 2gether(TM) App

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Providers

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Alok Kapoor

University of Massachusetts Medical School

Phone: 917-856-4538

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place