Endobronchial Ultrasound-Guided Transbronchial Needle-Aspiration With Suction in Obtaining Samples From Patients With Suspected Nodal Metastatic Lung Cancer

NCT ID: NCT04116970

Last Updated: 2026-02-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-08-31

Study Completion Date

2026-06-15

Brief Summary

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This trial studies how well endobronchial ultrasound-guided transbronchial needle-aspiration (EBUS-TBNA) with suction works in obtaining samples from patients with suspected lung cancer that has spread to the nodal. EBUS-TBNA samples obtained with additional suction may help to improve material-amounts and decrease blood contamination in the samples.

Detailed Description

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PRIMARY OBJECTIVES:

I. To evaluate if suction applied with a vacuum syringe during EBUS-TBNA sampling helps to obtain more material for molecular analyses.

OUTLINE:

Patients undergo bronchoscopy with EBUS-TBUA first without and then with applied vacuum.

Conditions

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Lung Carcinoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Diagnostic (bronchoscopy with EBUS-TBNA with/without vacuum)

Patients undergo bronchoscopy with EBUS-TBUA first without and then with applied vacuum.

Group Type EXPERIMENTAL

Bronchoscopy

Intervention Type PROCEDURE

Undergo bronchoscopy with EBUS-TBNA

Ultrasound-Guided Transbronchial Needle Aspiration

Intervention Type PROCEDURE

Undergo bronchoscopy with EBUS-TBNA

Interventions

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Bronchoscopy

Undergo bronchoscopy with EBUS-TBNA

Intervention Type PROCEDURE

Ultrasound-Guided Transbronchial Needle Aspiration

Undergo bronchoscopy with EBUS-TBNA

Intervention Type PROCEDURE

Other Intervention Names

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EBUS-TBNA Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration

Eligibility Criteria

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Inclusion Criteria

* Computed tomography (CT)-scan finding suspicious for lung cancer with nodal metastases
* Clinically stable to undergo diagnostic workup by bronchoscopy with endobronchial ultrasound

Exclusion Criteria

* Pregnant female
* Minors
* Prisoners
* Patients with contraindication for EBUS such as non-reversible anticoagulation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ohio State University Comprehensive Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Peter Kneuertz

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Peter Kneuertz, MD

Role: PRINCIPAL_INVESTIGATOR

Ohio State University Comprehensive Cancer Center

Locations

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Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Related Links

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Other Identifiers

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NCI-2018-02965

Identifier Type: REGISTRY

Identifier Source: secondary_id

OSU-18164

Identifier Type: -

Identifier Source: org_study_id

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