Efficacy of Different Respiratory Methods in Intensive Care
NCT ID: NCT04108585
Last Updated: 2019-09-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
108 participants
OBSERVATIONAL
2016-11-30
2019-09-30
Brief Summary
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Detailed Description
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It is a procedure with intubation complications and stimulation of the sympathetic system as well as tongue, lip and tooth injuries. In recent years, non-invasive respiratory support can be given with the aid of a mask or nasal cannula without intubation, which has stable hemodynamics, no secretion, can cough, adhere to orders, no face, neck and head injuries (difficulty in mask application) and the use of this method is rapidly increasing in intensive care units.
Non-invasive respiratory support can be provided by CPAP method. In this method, positive pressure blended oxygen can be given to the patient by using an oranasal mask. In the literature, the use of non-invasive CPAP has been reported to be the gold standard for respiratory failure, particularly in COPD and immunosuppressed patients. CPAP method is available as standard in mechanical ventilators used in intensive care. The major disadvantage of CPAP is the discomfort caused by the mask attached to the patient's face.
In recent years, high-flow oxygen therapy (HFO) has been introduced, and in this mode, high-flow oxygen therapy is applied to the patient with high frequency nasal route and especially successful in COPD patients. In this method, patient comfort is higher since there is no mask attachment. The HFO device is not available in the intensive care unit and is planned to be purchased with the support of TUBAP.
In our intensive care unit, patients are primarily given non-invasive respiratory support. Follow-up during this support is extremely important. Whether the non-invasive respiratory support is sufficient is determined by follow-up. Following non-invasive respiratory support, patients are followed up, respiratory frequency rises above 30-35 in the first hour, peripheral oxygen saturation \<90% decrease, systolic blood pressure increase 20%, 180 mmHg rise below 90 mmHg In case of an increase in heart rate of 20 beats / min, heart rate of more than 140 beats per minute, tachypnea, intercostal withdrawal, agitation and distress, the patient is intubated and respiratory support is applied invasively. Peripheral oxygen saturation, non-invasive blood pressure, heart rate, respiratory rate and respiratory rate are routinely used in our intensive care unit in the follow-up of patients. In the study, the patient papers will be followed and the respiratory support of the patients will be recorded and all follow-ups will be made from the patient follow-up chart. The aim of this study is to compare two different non-invasive breathing methods.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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HFO group
HFO therapy
HFO therapy
HFO therapy from mechanical ventilation
CPAP group
CPAP therapy
CPAP therapy
CPAP therapy from mechanical ventilation
Interventions
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HFO therapy
HFO therapy from mechanical ventilation
CPAP therapy
CPAP therapy from mechanical ventilation
Eligibility Criteria
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Inclusion Criteria
2. need oxygen therapy due to respiratory failure
3. Hemodynamic stability
4. Coughing
5. follow orders
6. face, neck and head without injury
Exclusion Criteria
2. pregnant women
3. nursing
18 Years
90 Years
ALL
No
Sponsors
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Trakya University
OTHER
Responsible Party
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Prof Mehmet Turan Inal
Member of Intensive Care
Locations
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Trakya University
Edirne, , Turkey (Türkiye)
Countries
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References
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Brotfain E, Zlotnik A, Schwartz A, Frenkel A, Koyfman L, Gruenbaum SE, Klein M. Comparison of the effectiveness of high flow nasal oxygen cannula vs. standard non-rebreather oxygen face mask in post-extubation intensive care unit patients. Isr Med Assoc J. 2014 Nov;16(11):718-22.
Other Identifiers
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TUTF-BAEK 2016-197
Identifier Type: -
Identifier Source: org_study_id