Trial Outcomes & Findings for Effect of Topical CBD Cream for Degenerative Hallux Disorders (NCT NCT04103814)

NCT ID: NCT04103814

Last Updated: 2024-10-15

Results Overview

Weekly visual analog system (VAS) pain scores will be measured daily for four weeks. The VAS pain score is a measure of pain severity. It is measured on a scale from 0 to 10, with 10 being the worst pain the patient has experienced. No patients completed full enrollment so no data was analyzed.

Recruitment status

TERMINATED

Study phase

PHASE2/PHASE3

Target enrollment

11 participants

Primary outcome timeframe

4 weeks

Results posted on

2024-10-15

Participant Flow

Participant milestones

Participant milestones
Measure
CBD Cream
Patients will be treated with CBD cream
Control
Patients will be treated with a placebo cream not containing CBD
Overall Study
STARTED
8
3
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
8
3

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

No data were collected/analyzed

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
CBD Cream
n=8 Participants
Patients will be randomized to CBD cream
Control
n=3 Participants
Patients will be randomized to a placebo cream without CBD
Total
n=11 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Age, Categorical
Between 18 and 65 years
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Age, Categorical
>=65 years
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Sex: Female, Male
Female
0 Participants
No data were collected/analyzed.
0 Participants
No data were collected/analyzed.
0 Participants
No data were collected/analyzed.
Sex: Female, Male
Male
0 Participants
No data were collected/analyzed.
0 Participants
No data were collected/analyzed.
0 Participants
No data were collected/analyzed.
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Race (NIH/OMB)
Asian
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Race (NIH/OMB)
Black or African American
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Race (NIH/OMB)
White
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Race (NIH/OMB)
More than one race
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
0 Participants
No data were collected/analyzed
Region of Enrollment
United States
8 participants
n=8 Participants
3 participants
n=3 Participants
11 participants
n=11 Participants

PRIMARY outcome

Timeframe: 4 weeks

Population: No data were analyzed for this outcome because there were no participants data collected.

Weekly visual analog system (VAS) pain scores will be measured daily for four weeks. The VAS pain score is a measure of pain severity. It is measured on a scale from 0 to 10, with 10 being the worst pain the patient has experienced. No patients completed full enrollment so no data was analyzed.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 4 weeks

Population: No data were analyzed for this outcome because there were no participants data collected

The foot function index (FFI) is a questionnaire that measures foot pain and disability. It is self-administered and consists of 23 items divided into 3 subscales (pain, disability, and activity limitation). The pain subcategory consists of 9 questions (scored out of 90) and is a measure of pain in different situations, such as walking with shoes versus barefoot. The disability subcategory consists of 9 questions (scored out of 90) and measures functional activities, such as difficulty walking upstairs. The activity limitation subcategory consists of 5 questions (scored out of 50) and measures limitations caused by the foot problem. All three subcategories are summed together to get a final number, with higher numbers indicating worse pain.

Outcome measures

Outcome data not reported

Adverse Events

Mg-CBDa Cream

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Placebo Cream

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr E Bailey Terhune

Rush University Medical cEnter

Phone: 8018249805

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place