Oscillating Positive Expiratory Pressure (OPEP) Therapy in Trauma Patients With Multiple Rib Fractures

NCT ID: NCT04100512

Last Updated: 2022-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-21

Study Completion Date

2023-10-31

Brief Summary

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To determine the efficacy of oscillatory positive expiratory pressure (OPEP) therapy on patients admitted through the trauma service line for rib fractures, as compared to incentive spirometry (IS).

Detailed Description

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Patients identified through screening procedures to fit the inclusion criteria will be approached, within 48 hours of floor admission, to participate in the study. Once written informed consent is obtained, participants will be randomized, in a 1:1 ratio, into either the IS or OPEP study group.

Each patient will be instructed on how to use the respiratory therapy device, either IS or OPEP, by research personnel and respiratory therapists. Participants will be instructed to record their compliance with the RT protocol in their respective patient diaries.

Respiratory Therapy will record FVC three times daily on all study participants until stable (FVC \> 1.5L x 4), then daily for up to 7 days or until discharge.

Participants will be contacted on day 30 from discharge, and administered a short questionnaire. All participants will be followed and monitored per standard of care, under the care and supervision of their treating provider teams.

Conditions

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Rib Fractures Respiratory Complication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Incentive spirometry

Each patient will be instructed on how to use the respiratory therapy device, either IS or OPEP, by research personnel and respiratory therapists. Participants will be instructed to record their compliance with the RT protocol in their respective patient diaries. Patient diaries will be collected upon discharge for analysis.

Group Type ACTIVE_COMPARATOR

Incentive spirometry

Intervention Type DEVICE

An incentive spirometer is a device that measures how deeply you can inhale (breathe in). It helps you take slow, deep breaths to expand and fill your lungs with air. The incentive spirometer is made up of a breathing tube, an air chamber, and an indicator.

Oscillating Positive Expiratory Pressure Device

Each patient will be instructed on how to use the respiratory therapy device, either IS or OPEP, by research personnel and respiratory therapists. Participants will be instructed to record their compliance with the RT protocol in their respective patient diaries. Patient diaries will be collected upon discharge for analysis.

Group Type EXPERIMENTAL

Oscillating Positive Expiratory Pressure Device

Intervention Type DEVICE

Aerobika® Oscillating Positive Expiratory Pressure (OPEP) device is a drug-free, easy to use, hand-held device with a proprietary pressure-oscillation dynamic that provides intermittent resistance and creates positive pressure and oscillations simultaneously. The Aerobika® OPEP device opens weak or collapsed airways to mobilize and assist mucociliary clearance to the upper airways where it can be coughed out.

Interventions

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Oscillating Positive Expiratory Pressure Device

Aerobika® Oscillating Positive Expiratory Pressure (OPEP) device is a drug-free, easy to use, hand-held device with a proprietary pressure-oscillation dynamic that provides intermittent resistance and creates positive pressure and oscillations simultaneously. The Aerobika® OPEP device opens weak or collapsed airways to mobilize and assist mucociliary clearance to the upper airways where it can be coughed out.

Intervention Type DEVICE

Incentive spirometry

An incentive spirometer is a device that measures how deeply you can inhale (breathe in). It helps you take slow, deep breaths to expand and fill your lungs with air. The incentive spirometer is made up of a breathing tube, an air chamber, and an indicator.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Greater than or equal to 18 years old
* Greater than or equal to 1 Rib Fracture
* Admitted to trauma services at Medical Center of the Rockies (MCR).

Exclusion Criteria

* Less than 18 years old
* Any physical injury that creates inability to functionally use devices
* Adults unable to consent or cooperate due to
* Dementia
* Confusion
* On ventilator support
* Moderate to severe Traumatic brain injury (Glasgow Coma Scale \< 12)
* Cervical spinal cord injury
* Women who are pregnant
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Monaghan Medical Corporation

UNKNOWN

Sponsor Role collaborator

Poudre Valley Health System

OTHER

Sponsor Role lead

Responsible Party

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Julie Dunn, M.D.

Trauma Research Medical Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Julie Dunn, MD

Role: PRINCIPAL_INVESTIGATOR

Trauma Research Medical Director

Locations

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Medical Center of the Rockies

Loveland, Colorado, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Julie Dunn, MD

Role: CONTACT

Phone: 970.624.1689

Email: [email protected]

Facility Contacts

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Julie Dunn, MD

Role: primary

Other Identifiers

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OPEP7292019

Identifier Type: -

Identifier Source: org_study_id