Evaluation of the Analytical Performance of ALLEGRO™ Instrument

NCT ID: NCT04096313

Last Updated: 2021-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

628 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-25

Study Completion Date

2021-12-15

Brief Summary

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To assess the performance of the Allegro in the hands of CLIA-Waived Point-of-Care users in at least three distinct Point-of-Care clinical settings and compare the performance characteristics to other accepted Point-of-Care methods and central laboratory reference methods.

To assess the Ease of Use of the Allegro in the hands of the intended CLIA-Waived Point-of-Care users. CLIA-Waived operators will be provided with all package insert sheets, a Quick Reference Guide poster and Instructions for Use. No training, coaching, or prompting will be provided other than clarifying the protocol.

Detailed Description

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Blood and urine tests are used in the assessment of diabetes and to guide clinical management. In the traditional model of care, blood samples are taken from patients at the clinic and are sent to the laboratory for analysis and the results may not be available for a number of hours/days after the clinic visit.

A new analyser has been developed (Allegro™) which allows the tests to be undertaken at the clinic, with the results available in a few minutes. This means that patients can get immediate feedback and that the doctors/nurses can adjust treatment before the patient leaves the clinic. It is obviously important that this analyzer performs to a similar degree of accuracy to the laboratory analyses.

The aim of this research study is to assess the accuracy of the Allegro™ analyzer compared to laboratory analyses on capillary and venous whole blood samples and urine samples. Three hundred sixty (360) patients with diabetes will be invited to give a venous blood sample, finger prick capillary blood sample and urine sample. The venous blood sample, finger prick capillary blood sample and urine sample will be analysed by both the Allegro™ analyser and laboratory analyses and the results compared. The Allegro™ results will not be used in the management of the patients' diabetes.

Conditions

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Diabetes Mellitus Kidney Diseases Metabolic Disease

Keywords

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HbA1c, Lipids, UACR

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

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HbA1c, Lipids, UACR

compare diagnostic tests to reference methods

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* patients with ordered HbA1c, lipid profile, and UACr

Exclusion Criteria

* pediatric
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Nova Biomedical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ronald Surowitz

Role: PRINCIPAL_INVESTIGATOR

Health Awareness, Inc

Allison Blomer, MA, MD

Role: PRINCIPAL_INVESTIGATOR

Health Awareness, Inc PSL

Jeremy Bleicher

Role: PRINCIPAL_INVESTIGATOR

South Florida Research Organization

Locations

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Health Awareness, Inc

Jupiter, Florida, United States

Site Status

South Florida Research Organization

Medley, Florida, United States

Site Status

Health Awareness, Inc PSL

Port Saint Lucie, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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NB19-ALL-NA-FDA

Identifier Type: -

Identifier Source: org_study_id