Trial Outcomes & Findings for Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating (NCT NCT04088097)

NCT ID: NCT04088097

Last Updated: 2024-10-10

Results Overview

Eating episodes will be assessed by questionnaire (Eating Disorder Examination questionnaire)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

50 participants

Primary outcome timeframe

Post (4 months)

Results posted on

2024-10-10

Participant Flow

Participant milestones

Participant milestones
Measure
Cognitive-Behavioral Therapy
Adapted Cognitive-Behavioral Therapy (CBT) for adolescents with binge eating or loss-of-control eating. Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating: Cognitive-behavioral therapy (CBT) developed for adolescents with binge eating or loss-of-control eating.
Control Condition
Educational materials related to adolescent health and nutrition. Control Condition: Educational and informational materials on adolescent health and nutrition.
Overall Study
STARTED
25
25
Overall Study
COMPLETED
23
21
Overall Study
NOT COMPLETED
2
4

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Cognitive-Behavioral Therapy
n=25 Participants
Adapted Cognitive-Behavioral Therapy (CBT) for adolescents with binge eating or loss-of-control eating. Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating: Cognitive-behavioral therapy (CBT) developed for adolescents with binge eating or loss-of-control eating.
Control Condition
n=25 Participants
Educational materials related to adolescent health and nutrition. Control Condition: Educational and informational materials on adolescent health and nutrition.
Total
n=50 Participants
Total of all reporting groups
Age, Continuous
14.20 years
STANDARD_DEVIATION 1.66 • n=5 Participants
14.88 years
STANDARD_DEVIATION 1.33 • n=7 Participants
14.54 years
STANDARD_DEVIATION 1.53 • n=5 Participants
Sex/Gender, Customized
Male
8 Participants
n=5 Participants
11 Participants
n=7 Participants
19 Participants
n=5 Participants
Sex/Gender, Customized
Female
17 Participants
n=5 Participants
13 Participants
n=7 Participants
30 Participants
n=5 Participants
Sex/Gender, Customized
Non Binary
0 Participants
n=5 Participants
1 Participants
n=7 Participants
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
3 Participants
n=5 Participants
3 Participants
n=7 Participants
6 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
22 Participants
n=5 Participants
22 Participants
n=7 Participants
44 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
Race (NIH/OMB)
Asian
1 Participants
n=5 Participants
1 Participants
n=7 Participants
2 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
3 Participants
n=5 Participants
6 Participants
n=7 Participants
9 Participants
n=5 Participants
Race (NIH/OMB)
White
17 Participants
n=5 Participants
18 Participants
n=7 Participants
35 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
3 Participants
n=5 Participants
0 Participants
n=7 Participants
3 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Region of Enrollment
United States
25 Participants
n=5 Participants
25 Participants
n=7 Participants
50 Participants
n=5 Participants
Binge Eating Episodes
12.04 episodes of behavior
STANDARD_DEVIATION 9.19 • n=5 Participants
13.57 episodes of behavior
STANDARD_DEVIATION 19.11 • n=7 Participants
12.77 episodes of behavior
STANDARD_DEVIATION 14.62 • n=5 Participants

PRIMARY outcome

Timeframe: Post (4 months)

Eating episodes will be assessed by questionnaire (Eating Disorder Examination questionnaire)

Outcome measures

Outcome measures
Measure
Cognitive-Behavioral Therapy
n=21 Participants
Adapted Cognitive-Behavioral Therapy (CBT) for adolescents with binge eating or loss-of-control eating. Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating: Cognitive-behavioral therapy (CBT) developed for adolescents with binge eating or loss-of-control eating.
Control Condition
n=19 Participants
Educational materials related to adolescent health and nutrition. Control Condition: Educational and informational materials on adolescent health and nutrition.
Binge (Loss-of-control) Eating Episode Frequency
1.52 episodes of behavior
Standard Deviation 2.09
6.05 episodes of behavior
Standard Deviation 10.35

PRIMARY outcome

Timeframe: Post (4 months)

Percent BMI change

Outcome measures

Outcome measures
Measure
Cognitive-Behavioral Therapy
n=21 Participants
Adapted Cognitive-Behavioral Therapy (CBT) for adolescents with binge eating or loss-of-control eating. Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating: Cognitive-behavioral therapy (CBT) developed for adolescents with binge eating or loss-of-control eating.
Control Condition
n=20 Participants
Educational materials related to adolescent health and nutrition. Control Condition: Educational and informational materials on adolescent health and nutrition.
Weight (e.g., Percent Loss)
.02 percentage of baseline BMI
Standard Deviation .13
.01 percentage of baseline BMI
Standard Deviation .06

SECONDARY outcome

Timeframe: Short-Term Follow-Up (3 months after end of treatment)

Eating episodes will be assessed by questionnaire (Eating Disorder Examination Questionnaire)

Outcome measures

Outcome measures
Measure
Cognitive-Behavioral Therapy
n=23 Participants
Adapted Cognitive-Behavioral Therapy (CBT) for adolescents with binge eating or loss-of-control eating. Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating: Cognitive-behavioral therapy (CBT) developed for adolescents with binge eating or loss-of-control eating.
Control Condition
n=17 Participants
Educational materials related to adolescent health and nutrition. Control Condition: Educational and informational materials on adolescent health and nutrition.
Binge (Loss-of-control) Eating Episode Frequency
2.04 episodes of behavior
Standard Deviation 2.92
5.94 episodes of behavior
Standard Deviation 9.59

SECONDARY outcome

Timeframe: Short-Term Follow-Up (3 months after end of treatment)

Percent BMI change

Outcome measures

Outcome measures
Measure
Cognitive-Behavioral Therapy
n=23 Participants
Adapted Cognitive-Behavioral Therapy (CBT) for adolescents with binge eating or loss-of-control eating. Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating: Cognitive-behavioral therapy (CBT) developed for adolescents with binge eating or loss-of-control eating.
Control Condition
n=18 Participants
Educational materials related to adolescent health and nutrition. Control Condition: Educational and informational materials on adolescent health and nutrition.
Weight (e.g., Percent Loss)
.02 percentage of baseline BMI
Standard Deviation .14
.01 percentage of baseline BMI
Standard Deviation .06

Adverse Events

Cognitive-Behavioral Therapy

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control Condition

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr Janet Lydecker

Yale University

Phone: 2037374299

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place