A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HIP1801 in Healthy Male Subjects.

NCT ID: NCT04084197

Last Updated: 2019-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

61 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-12-19

Study Completion Date

2019-01-04

Brief Summary

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An open-label, randomized, single-dose crossover study to evaluate the pharmacokinetics, safety and tolerability of HIP1801 in healthy male subjects.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Sequence 1

Period 1 : Fasted state + HIP1402, Period 2 : Fasted state + HIP1801

Group Type EXPERIMENTAL

HIP1402

Intervention Type DRUG

Tamsulosin (HanmiTams Capsule) 0.4mg

HIP1801

Intervention Type DRUG

Tamsulosin 0.4mg

Sequence 2

Period 1 : Fasted state + HIP1801, Period 2 : Fasted state + HIP1402

Group Type EXPERIMENTAL

HIP1402

Intervention Type DRUG

Tamsulosin (HanmiTams Capsule) 0.4mg

HIP1801

Intervention Type DRUG

Tamsulosin 0.4mg

Sequence 3

High fat diet + HIP1402, Period 2 : High fat diet + HIP1801

Group Type EXPERIMENTAL

HIP1402

Intervention Type DRUG

Tamsulosin (HanmiTams Capsule) 0.4mg

HIP1801

Intervention Type DRUG

Tamsulosin 0.4mg

Sequence 4

High fat diet + HIP1801, Period 2 : High fat diet + HIP1402

Group Type EXPERIMENTAL

HIP1402

Intervention Type DRUG

Tamsulosin (HanmiTams Capsule) 0.4mg

HIP1801

Intervention Type DRUG

Tamsulosin 0.4mg

Interventions

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HIP1402

Tamsulosin (HanmiTams Capsule) 0.4mg

Intervention Type DRUG

HIP1801

Tamsulosin 0.4mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Age 19\~45 years in healthy male volunteers
2. BMI is more than 18.5 kg/m\^2 , no more than 29.9 kg/m\^2
3. Subjects who have ability to comprehend the objectives, contents of study and property of study drug before participating in trial and have willingness to sign of informed consent in writing

Exclusion Criteria

1. Presence of medical history or a concurrent disease that may interfere with treatment and safety assessment or completion of this clinical study, including clinically significant disorders in digestive system, neuropsychiatric system, endocrine system, liver, cardiovascular system
2. Subjects who judged ineligible by the investigator
Minimum Eligible Age

19 Years

Maximum Eligible Age

45 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hanmi Pharmaceutical Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Korea University Anam Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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HM-TOD-101

Identifier Type: -

Identifier Source: org_study_id

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