Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers

NCT ID: NCT04077372

Last Updated: 2023-01-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-09-16

Study Completion Date

2020-10-11

Brief Summary

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The purpose of the study is to determine whether standardized implementation of a scripted template for discussing important issues that arise near the end of life improves the care of those who have advanced cancer.

Detailed Description

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Primary Objective: To determine whether the Serious Illness Conversation Guide will improve the consistency with which providers have and document conversations regarding patients' goals and priorities as they near the end of life.

Secondary Objectives: 1. To assess whether having conversations as per this model will improve the quality of care near the end of life as determined by appropriate care in concordance with their goals of care.

2\. To assess whether having conversations as per this model will improve patient Quality of Life (QOL) as per a validated scale.

3\. To assess in patients with concordant care whether this model will improve patient QOL as per a validated scale 4. To assess provider opinions about end-of-life conversations.

Conditions

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Gastrointestinal Cancer Colorectal Cancer Pancreatic Adenocarcinoma Gastric Cancer Esophageal Cancer Cholangiocarcinoma Hepatocellular Carcinoma Neuroendocrine Tumors GIST, Malignant

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Serious illness conversation guide (SICG)

Patients have "serious illness conversation" within 3 wks of randomization and every 3 months thereafter.

Group Type EXPERIMENTAL

Serious Illness Conversation Guide (SICG)

Intervention Type BEHAVIORAL

The Serious Illness Conversation Guide (SICG) is a structured communication template designed to provide effective tool in initiating advanced care planning discussion with patients.

Quality of Life (QOL) survey

Intervention Type BEHAVIORAL

Quality of life survey by questionnaire (FACT-G) given every three months

Conversations by treating team

Patients have conversations as determined by treating team (but not using SICG tool).

Group Type ACTIVE_COMPARATOR

Quality of Life (QOL) survey

Intervention Type BEHAVIORAL

Quality of life survey by questionnaire (FACT-G) given every three months

Interventions

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Serious Illness Conversation Guide (SICG)

The Serious Illness Conversation Guide (SICG) is a structured communication template designed to provide effective tool in initiating advanced care planning discussion with patients.

Intervention Type BEHAVIORAL

Quality of Life (QOL) survey

Quality of life survey by questionnaire (FACT-G) given every three months

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Patients with metastatic colorectal cancer whose tumor has progressed on both FOLFOX and FOLFIRI.
* Exception: Patients with metastatic colorectal cancer whose tumors demonstrate a BRAF V600E mutation may be enrolled regardless of prior chemotherapy.
* Exception: Patients whose tumors are MSI-H must have experience progression through immunotherapy in addition to the therapies mentioned above.
* Patients with metastatic pancreatic adenocarcinoma.
* Patients with metastatic gastric or esophageal cancer whose tumor has progressed through first-line chemotherapy of any type.
* Patients with metastatic cholangiocarcinoma whose tumor has progressed through first-line chemotherapy of any type.
* Patients with metastatic hepatocellular carcinoma whose tumor has progressed through PD1 blockade.
* Patients with metastatic high-grade neuroendocrine tumor.
* A patient with a metastatic GIST that has progressed through first-line tyrosine kinase inhibitor.
* Expected life expectancy of at least one month

Exclusion Criteria

* Any patient not meeting the above criteria
* Non-English speaking patients
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tyler P Johnson, MD

Role: PRINCIPAL_INVESTIGATOR

Stanford University

Locations

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Stanford Cancer Center

Stanford, California, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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VAR0179

Identifier Type: OTHER

Identifier Source: secondary_id

IRB-51256

Identifier Type: OTHER

Identifier Source: secondary_id

NCI-2019-07235

Identifier Type: OTHER

Identifier Source: secondary_id

IRB-51256

Identifier Type: -

Identifier Source: org_study_id

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