Prevalence of Sonographic Abnormalities of Joints and Entheses in Psoriasis Patients With or Without Musculoskeletal Complains

NCT ID: NCT04074070

Last Updated: 2023-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-02-18

Study Completion Date

2020-09-30

Brief Summary

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The objectives of this study are:

* to estimate the prevalence and severity of inflammatory (synovitis, tenosynovitis, enthesitis, dactylitis) and structural (erosions, osteophytes, enthesophytes, cortical irregularities ) ultrasound lesions in psoriasis patients with or without related musculoskeletal symptoms;
* to compare them to healthy subjects or patients suffering from rheumatoid arthritis and osteoarthritis.

Detailed Description

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Conditions

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Psoriasis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Psoriasis with and without musculoskeletal complains

psoriasis with and without musculoskeletal complains

Ultrasound examination

Intervention Type OTHER

Ultrasound examination of joints, tendons and entheses.

Healthy individuals

Ultrasound examination

Intervention Type OTHER

Ultrasound examination of joints, tendons and entheses.

Psoriatic arthritis

Ultrasound examination

Intervention Type OTHER

Ultrasound examination of joints, tendons and entheses.

Interventions

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Ultrasound examination

Ultrasound examination of joints, tendons and entheses.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years;
* Psoriasis diagnosed by a dermatologist;
* Able to participate in the study;
* Informed consent signed.

Exclusion Criteria

\- Chronic disease likely to cause musculoskeletal symptoms (connective tissue diseases, inflammatory bowel diseases, overload disorders, crystal related arthritis, septic arthritis...).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Maria-Antonietta D'Agostino, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Rheumatology Department, Ambroise Paré Hospital

Locations

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Rheumatology Department, Ambroise Paré Hospital

Boulogne-Billancourt, , France

Site Status

Countries

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France

Other Identifiers

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2018-A02781-54

Identifier Type: REGISTRY

Identifier Source: secondary_id

APHP190683

Identifier Type: -

Identifier Source: org_study_id

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