Kentucky Women's Justice Community Opioid Innovation Network

NCT ID: NCT04069624

Last Updated: 2025-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

900 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-17

Study Completion Date

2026-04-30

Brief Summary

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This trial will test the effectiveness of delivering medication for opioid use disorder (MOUD) pre-treatment via telehealth, alone and with peer navigation, to increase MOUD initiation and maintenance in the community following jail release. This trial will focus on incarcerated women in 6 experimental and 3 control sites in Kentucky. Enrollment is not open to the general public.

Detailed Description

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This study will incorporate random assignment for two study conditions: medication for opioid use disorder (MOUD) PreTreatment Telehealth or MOUD PreTreatment Telehealth with Peer Navigation using a rigorous randomized block design. Women in the experimental conditions will be stratified by sites (6 sites; 3 urban and 3 non-urban) and by offender classification level of felony versus misdemeanor (due to potential differences in community supervision). Three comparison sites with existing jail-based MOUD treatment for women will not be randomized but will be included in analyses within planned, non-randomized comparisons.

1. MOUD PreTreatment Telehealth: Participants who screen positive for moderate to high-risk opioid use and complete the baseline interview will be connected via telehealth to the community MOUD provider for a psychosocial assessment. The study data coordinator will assist with linking the participant to the community MOUD provider via telehealth, as well as collecting initial in-person biological specimens for medical evaluation. The psychosocial assessment with the community MOUD provider will involve a more detailed examination of OUD using the Diagnostic and Statistical Manual of Mental Disorders (DSM) 5 criteria. Type of medication (naltrexone, buprenorphine, or methadone) will depend on the psychosocial assessment and medical evaluation. Indications for the most appropriate course of treatment will be determined by the community MOUD provider in conjunction with the study participant. Women in this condition will also receive general education about MOUD options including risks and benefits, and they will be given the opportunity to ask questions about the medication. The community MOUD provider will also use motivational interviewing to assess each woman's readiness to engage in MOUD and to better understand possible barriers to MOUD utilization. At the end of the education session, the study participant and the MOUD community provider will develop a re-entry plan for ongoing care, which will include a plan for insurance coverage of medications in the community.
2. MOUD PreTreatment Telehealth + Peer Navigation: In addition to MOUD PreTreatment Telehealth, women in this arm will be connected with a peer, a woman in recovery who is employed by Voices of Hope (VOH) in Lexington, KY. Peer Navigators will be located in Lexington through a partnership with VOH. VOH is a non-profit recovery support organization which provides peer recovery support services. In conjunction with the study data coordinators, the Peer Navigator will schedule an initial session via telehealth with the participant, assist with scheduling a follow-up appointment with the community MOUD provider, and provide recovery support for community MOUD initiation and maintenance. Peer Navigators will be certified Peer Support Specialists trained and supervised by VOH in accordance with state statutory requirements. When a woman returns to the community, Peer Navigators will engage her in weekly telephone recovery services (TRS) for 12 weeks, which may include identifying personal goals and strength-based, practical strategies for success. In addition to MOUD linkages to care, Peer Navigators will suggest strategies to maintain sobriety and improve recovery capital, including safe housing, transportation, financial counseling, continued education, employment skills, and sober social activities.
3. Services as Usual: Women in this arm will not be randomized, but will receive substance abuse treatment as usual in three comparison jail sites. Each of these jails has a women's substance abuse program (SAP) managed by the Kentucky Department of Corrections (KY-DOC with the option to initiate MOUD prior to jail release. These programs operate as modified therapeutic communities with transitional support following release.

Conditions

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Opioid-use Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Services as Usual (SAU)

Substance abuse program (SAP) managed by the Kentucky Department of Corrections, with the option to initiate MOUD prior to jail release.

Group Type ACTIVE_COMPARATOR

Services as Usual

Intervention Type OTHER

Medications to treat opioid use disorder (MOUD) pre-treatment.

MOUD Pre-Treatment Telehealth

Telehealth connection to a community MOUD provider.

Group Type EXPERIMENTAL

MOUD Pre-Treatment Telehealth

Intervention Type BEHAVIORAL

Opioid use disorder (OUD) assessment, medical evaluation, and medications to treat opioid use disorder (MOUD) education with a MOUD provider during incarceration via telehealth

MOUD Pre-Treatment Telehealth and Peer Navigator

Telehealth connection to a community MOUD provider, in addition to a peer navigator

Group Type EXPERIMENTAL

MOUD Pre-Treatment Telehealth and Peer Navigator

Intervention Type BEHAVIORAL

Opioid use disorder (OUD) assessment, medical evaluation, and medications to treat opioid use disorder (MOUD) education with a MOUD provider during incarceration via telehealth. Additionally, participants will be connected with a Peer Navigator who will meet with them via telehealth prior to release and provide ongoing support by telephone post-release.

Interventions

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MOUD Pre-Treatment Telehealth

Opioid use disorder (OUD) assessment, medical evaluation, and medications to treat opioid use disorder (MOUD) education with a MOUD provider during incarceration via telehealth

Intervention Type BEHAVIORAL

MOUD Pre-Treatment Telehealth and Peer Navigator

Opioid use disorder (OUD) assessment, medical evaluation, and medications to treat opioid use disorder (MOUD) education with a MOUD provider during incarceration via telehealth. Additionally, participants will be connected with a Peer Navigator who will meet with them via telehealth prior to release and provide ongoing support by telephone post-release.

Intervention Type BEHAVIORAL

Services as Usual

Medications to treat opioid use disorder (MOUD) pre-treatment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ASSIST opioid (prescription or street) score of 4+
* Willingness to participate in MOUD pre-treatment
* Incarceration period of at least 7 days

Exclusion Criteria

• Cognitive impairment
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

Michele Staton

OTHER

Sponsor Role lead

Responsible Party

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Michele Staton

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Michele Staton, MSW, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Kentucky

Locations

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Hardin County Detention Center

Elizabethtown, Kentucky, United States

Site Status

Harlan County Detention Center

Harlan, Kentucky, United States

Site Status

Henderson County Detention Center

Henderson, Kentucky, United States

Site Status

Marion County Detention Center

Lebanon, Kentucky, United States

Site Status

Grayson County Detention Center

Leitchfield, Kentucky, United States

Site Status

Laurel County Correctional Center

London, Kentucky, United States

Site Status

Pike County Detention Center

Pikeville, Kentucky, United States

Site Status

Shelby County Detention Center

Shelbyville, Kentucky, United States

Site Status

Grant County Detention Center

Williamstown, Kentucky, United States

Site Status

Countries

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United States

References

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Staton M, Levi M, Winston E, B Oser C, Fallin-Bennett A, Dickson M, Matthew Webster J, Leukefeld C, Tillson M. Examining use of telehealth in jails: linking women to community OUD services. BMC Womens Health. 2024 Oct 4;24(1):549. doi: 10.1186/s12905-024-03394-4.

Reference Type DERIVED
PMID: 39367439 (View on PubMed)

Other Identifiers

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1UG1DA050069

Identifier Type: NIH

Identifier Source: secondary_id

View Link

51656

Identifier Type: -

Identifier Source: org_study_id

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