A Study to Assess How Well Certolizumab Pegol Works in Patients With Moderate to Severe Plaque Psoriasis as Part of Routine Clinical Practice

NCT ID: NCT04053881

Last Updated: 2023-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

412 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-08-21

Study Completion Date

2022-12-02

Brief Summary

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The purpose of the study is to assess the effectiveness of certolizumab pegol in patients with moderate to severe plaque psoriasis as part of routine clinical practice.

Detailed Description

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Conditions

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Plaque Psoriasis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Certolizumab pegol

Plaque psoriasis patients who have been newly prescribed certolizumab pegol (CZP).

Certolizumab pegol

Intervention Type DRUG

Active Substance: Certolizumab Pegol Pharmaceutical Form: Prefilled syringe Concentration: 200 mg/ml Route of Administration: Subcutaneous injection

Interventions

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Certolizumab pegol

Active Substance: Certolizumab Pegol Pharmaceutical Form: Prefilled syringe Concentration: 200 mg/ml Route of Administration: Subcutaneous injection

Intervention Type DRUG

Other Intervention Names

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Cimzia CDP870

Eligibility Criteria

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Inclusion Criteria

* The patient is ≥18 years of age at observational point 1
* The patient must have a clinical diagnosis of moderate to severe Plaque psoriasis according to the diagnostic criteria used by the physician in routine clinical practice
* The patient has an available PASI assessment prior to the first certolizumab pegol dose according to the standard of care
* The patient must be newly prescribed with certolizumab pegol
* If a patient is participating in an ongoing investigational study, then he/she will not be able to take part in this study

Exclusion Criteria

Not applicable
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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UCB Biopharma SRL

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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UCB Cares

Role: STUDY_DIRECTOR

001 844 599 2273 (UCB)

Locations

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Ps0026 101

Brussels, , Belgium

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Brussels, , Belgium

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Brussels, , Belgium

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Leuven, , Belgium

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Maldegem, , Belgium

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Mons, , Belgium

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Namur, , Belgium

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London, , Canada

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London, , Canada

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Markham, , Canada

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Newmarket, , Canada

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St. John's, , Canada

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Toronto, , Canada

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Waterloo, , Canada

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Winnipeg, , Canada

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Prague, , Czechia

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Prague, , Czechia

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Uherské Hradiště, , Czechia

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Amiens, , France

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Lorient, , France

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Poitiers, , France

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Rennes, , France

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Toulon, , France

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Bielefeld, , Germany

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Bogen, , Germany

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Dresden, , Germany

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Düren, , Germany

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Freiburg im Breisgau, , Germany

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Gladbeck, , Germany

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Hamburg, , Germany

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Karlsruhe, , Germany

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Leipzig, , Germany

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Magdeburg, , Germany

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Memmingen, , Germany

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Merzig, , Germany

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München, , Germany

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München, , Germany

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Nuremberg, , Germany

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Potsdam, , Germany

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Quedlinburg, , Germany

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Remscheid, , Germany

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Athens, , Greece

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Athens, , Greece

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Athens, , Greece

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Chaïdári, , Greece

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Larissa, , Greece

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Pátrai, , Greece

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Piraeus, , Greece

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Thessaloniki, , Greece

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Thessaloniki, , Greece

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Bari, , Italy

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Bologna, , Italy

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Brescia, , Italy

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Catania, , Italy

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Florence, , Italy

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Genova, , Italy

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L’Aquila, , Italy

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Napoli, , Italy

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Roma, , Italy

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Roma, , Italy

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San Donato Milanese, , Italy

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Torino, , Italy

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Torrette DI Ancona, , Italy

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Badalona, , Spain

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Barcelona, , Spain

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Barcelona, , Spain

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Pontevedra, , Spain

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Sant Joan Despí, , Spain

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Vigo, , Spain

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Bradford, , United Kingdom

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Dunfermline, , United Kingdom

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Glasgow, , United Kingdom

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Hertfordshire, , United Kingdom

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Kingston upon Thames, , United Kingdom

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Leeds, , United Kingdom

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Newcastle upon Tyne, , United Kingdom

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Salford, , United Kingdom

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Wakefield, , United Kingdom

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York, , United Kingdom

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Countries

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Belgium Canada Czechia France Germany Greece Italy Spain United Kingdom

References

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Korge B, Vanhooteghem O, Lynde CW, Machovcova A, Perrussel M, Lazaridou E, Marasca C, Sarro DV, Pousa ID, Fierens F, Williams P, Shimizu S, Heidbrede T, Warren RB. Certolizumab Pegol for the Treatment of Plaque Psoriasis in Routine Clinical Practice: One-Year Results from the CIMREAL Study. Dermatol Ther (Heidelb). 2024 Aug;14(8):2077-2092. doi: 10.1007/s13555-024-01210-3. Epub 2024 Jun 27.

Reference Type DERIVED
PMID: 38937404 (View on PubMed)

Other Identifiers

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PS0026

Identifier Type: -

Identifier Source: org_study_id

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