Endoscopic Characterization of Colorectal Neoplasia With the Different Published Classifications

NCT ID: NCT04048447

Last Updated: 2019-08-07

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 206 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-08-01
• Study Completion Date: 2019-08-01

Brief Summary

Endoscopic characterization is now essential in front of a colorectal lesion to predict its histology and choose the best therapeutic strategy. Different classifications have been proposed to predict histology depending on the endoscopic aspect. Thus, the aspect of the shape of the lesion is described in the Paris classification, the aspect of the mucosal pattern in Kudo's classification and the vascular pattern in Sano's one. Recently, classifications combining several color and mucosal and vascular pattern criteria have been described as the NICE classification or even more recently the Japanese JNET classification. However, although the interest in combining the Paris, Sano and Kudo criteria has recently shown its interest, there was not yet an overall classification covering all the published criteria. We have created a synthetic classification called CONECCT grouping the different criteria for an initial educational purpose. We have demonstrated that this tool allows interns and gastroenterologists to progress in the histological prediction of colorectal lesions presented in the form of photo files. Nevertheless, comparative data of the performances of those different classifications to predict the histology and the concordance intra and inter-observer have never been published. To validate this CONECCT classification, we created this comparative study evaluating the endoscopic characterization performances of these different classifications in terms of histological prediction and intra- and interobserver concordance in a group of gastroenterologists with varying levels of expertise in front of colorectal lesions presented in the form of photographic records.

Conditions

Colorectal Neoplasia

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• The participants were gastroenterologist doctors (experts, general or internal).
• Lesions presented were resected endoscopically after completion of a picture file.
• Pathology available for presented lesions.
• Participants signed informed consent and voluntarily participated in the characterization of these 206 lesions.

Exclusion Criteria

• None

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hôpital Edouard Herriot

OTHER

Sponsor Role: lead

Responsible Party

Jean Christophe Saurin

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Edouard Herriot Hospital

Lyon, Auvergne-Rhône-Alpes, France

Countries

France

Other Identifiers

SFED PROTOCOL

Identifier Type: -

Identifier Source: org_study_id