Nicotine Patch as an Adjunctive Intervention to Reduce Secondhand Smoke Among NICU Families

NCT ID: NCT04045964

Last Updated: 2024-12-11

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-29

Study Completion Date

2018-06-28

Brief Summary

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The purpose of this study was to explore the potential for directly targeting smoking cessation, regardless of motivation level, in a subsample of neonatal intensive care unit (NICU) parents with the ultimate goal of reducing secondhand smoke (SHS) in their homes.

Detailed Description

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Conditions

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Environmental Tobacco Smoke Smoking Cessation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Motivational advice and free NRT

Group Type EXPERIMENTAL

nicotine replacement therapy (NRT)

Intervention Type DRUG

Participants were provided with either 2 weeks of 14-mg or 21-mg transdermal nicotine patches for every smoker in the home

motivational advice

Intervention Type BEHAVIORAL

Received two in-hospital motivational advice sessions by a research associate (RA). The RA adapted session content from a previous tobacco-smoke exposure protocol

Quitline referral

Group Type ACTIVE_COMPARATOR

Quitline referral

Intervention Type BEHAVIORAL

Quitline participants received information about tobacco-smoke exposure reduction and a referral to a tobacco Quitline.

Interventions

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nicotine replacement therapy (NRT)

Participants were provided with either 2 weeks of 14-mg or 21-mg transdermal nicotine patches for every smoker in the home

Intervention Type DRUG

motivational advice

Received two in-hospital motivational advice sessions by a research associate (RA). The RA adapted session content from a previous tobacco-smoke exposure protocol

Intervention Type BEHAVIORAL

Quitline referral

Quitline participants received information about tobacco-smoke exposure reduction and a referral to a tobacco Quitline.

Intervention Type BEHAVIORAL

Other Intervention Names

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nicotine patch

Eligibility Criteria

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Inclusion Criteria

* Eligible mothers of any age or ethnic background must have an infant that is at least 1 week prior to the estimated date of hospital discharge in the NICU (ensuring time for the intervention)
* report that a household resident smokes at least 5 cigarettes per day, on average, within the 2 months preceding the screening visit
* agree to attend intervention sessions
* live within 50 miles of our center
* and have access to a telephone

Exclusion Criteria

* Mothers were ineligible if they met criteria for severe cognitive, and/or psychiatric impairment, per judgment of NICU and research staff, that precludes cooperation with study protocol
* were unable to read, write, and speak English
* were unable or unwilling to provide signed consent for participation
* and were unable or unwilling to meet study requirements for data collection and intervention purposes.
* Within the month immediately preceding the screening visit, use of any form of tobacco or nicotine products other than cigarettes (e.g., e-cigarettes, chewing tobacco, etc.) on 3 or more days within a week if the individual refuses to refrain from such tobacco use during the course of the study
* Current use of NRT or enrollment (or plans to enroll) in another smoking cessation program in the next 3 months
* Uncontrolled hypertension (systolic blood pressure \[SBP\] greater than 180 or diastolic blood pressure \[DBP\] greater than 110)
* History of severe cardiovascular (stroke, heart attack), kidney (e.g. chronic or acute kidney failure) or liver disease, or other unstable disease in the last 3 months
* History of hypersensitivity or allergic reaction to NRT or similar chemical classes or any component of these formulations (including allergy to latex)
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

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Angela L Stotts

Professor and Vice Chair for Research (Department of Family & Community Medicine)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Angela L Stotts, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Locations

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University of Texas Health Science Center at Houston

Houston, Texas, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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HSC-MS-11-0641(Substudy)

Identifier Type: -

Identifier Source: org_study_id