Mindfulness Based Smoking Cessation Among Cancer Survivors

NCT ID: NCT04038255

Last Updated: 2025-09-09

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE4

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-09-28

Study Completion Date

2024-05-19

Brief Summary

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This study will examine the effect of a mindfulness-based smoking cessation program among cancer survivors.

Detailed Description

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Conditions

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Tobacco Smoking

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Usual Care

Participants in this group will receive a brief advice to quit smoking, 6-week supplies of nicotine replacement therapy (NRT), and self-help materials to quit smoking.

Group Type ACTIVE_COMPARATOR

Nicoderm C-Q Transdermal Product

Intervention Type DRUG

6 weeks of nicotine replacement therapy patches

Brief advice on quitting smoking

Intervention Type BEHAVIORAL

Standard advice on how to quit smoking.

Self-help smoking cessation materials

Intervention Type BEHAVIORAL

Written materials on how to quit smoking including contact info for state tobacco quitline.

Craving-to-Quit app

Participants in this group will receive one "in-person" or online orientation session, 6-week supply of NRT, the "Craving-to-Quit" app, and two brief follow-up phone calls.

Group Type EXPERIMENTAL

Nicoderm C-Q Transdermal Product

Intervention Type DRUG

6 weeks of nicotine replacement therapy patches

Orientation session

Intervention Type BEHAVIORAL

This session will occur 2 weeks before quit date. It will be moderated by a certified instructor in MT, and will last approximately 90 min. During the session, participants will learn the purpose, format, and procedures of the study, provide electronic informed consent which will be audio-recorded with their permission, and complete the baseline assessment.

Craving-to-Quit app

Intervention Type BEHAVIORAL

The app is comprised of 22 modules for 22 days, 5-15 minutes each, designed to teach MT using audio, video, and animation. The app also includes other features such as social support (quit friend sign-ups, the tip of the week), activity feed (to track interaction with the app), and my morning stats (to track smoking).

Two brief follow-up phone calls

Intervention Type BEHAVIORAL

The first phone call will occur one day before the quit date to remind participants about their quit date and provide support. The second will occur at the end of treatment (around day 60 after quit date) to review progress, provide support, and schedule the 3-month follow-up visit. Each phone call will last approximately 15 minutes.

Group Mindfulness Training

Participants in this group will receive twice weekly group sessions (eight total during 4 weeks) that were manualized and delivered by instructors experienced in Mindfulness Training (MT) (a single therapist with \>4 years of training in MT).

Group Type EXPERIMENTAL

Nicoderm C-Q Transdermal Product

Intervention Type DRUG

6 weeks of nicotine replacement therapy patches

Orientation session

Intervention Type BEHAVIORAL

This session will occur 2 weeks before quit date. It will be moderated by a certified instructor in MT, and will last approximately 90 min. During the session, participants will learn the purpose, format, and procedures of the study, provide electronic informed consent which will be audio-recorded with their permission, and complete the baseline assessment.

Group MT sessions

Intervention Type BEHAVIORAL

Total of eight group sessions (twice a week) during 4 weeks. The overarching theme of momentary awareness and acceptance of cravings and affect (e.g., stress, anxiety etc.) will be introduced and reinforced in complementary ways throughout the training. Each session will last 45-60 minutes.

Interventions

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Nicoderm C-Q Transdermal Product

6 weeks of nicotine replacement therapy patches

Intervention Type DRUG

Orientation session

This session will occur 2 weeks before quit date. It will be moderated by a certified instructor in MT, and will last approximately 90 min. During the session, participants will learn the purpose, format, and procedures of the study, provide electronic informed consent which will be audio-recorded with their permission, and complete the baseline assessment.

Intervention Type BEHAVIORAL

Craving-to-Quit app

The app is comprised of 22 modules for 22 days, 5-15 minutes each, designed to teach MT using audio, video, and animation. The app also includes other features such as social support (quit friend sign-ups, the tip of the week), activity feed (to track interaction with the app), and my morning stats (to track smoking).

Intervention Type BEHAVIORAL

Two brief follow-up phone calls

The first phone call will occur one day before the quit date to remind participants about their quit date and provide support. The second will occur at the end of treatment (around day 60 after quit date) to review progress, provide support, and schedule the 3-month follow-up visit. Each phone call will last approximately 15 minutes.

Intervention Type BEHAVIORAL

Group MT sessions

Total of eight group sessions (twice a week) during 4 weeks. The overarching theme of momentary awareness and acceptance of cravings and affect (e.g., stress, anxiety etc.) will be introduced and reinforced in complementary ways throughout the training. Each session will last 45-60 minutes.

Intervention Type BEHAVIORAL

Brief advice on quitting smoking

Standard advice on how to quit smoking.

Intervention Type BEHAVIORAL

Self-help smoking cessation materials

Written materials on how to quit smoking including contact info for state tobacco quitline.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Be 18 years and older
* Cancer survivors (based on the NCI definition - "a person is considered to be a survivor from the time of diagnosis until the end of life" National Cancer Institute Dictionary of Cancer Terms, 2014)
* Cancer patients currently in active treatment
* Have smoked ≥ 5 cigarettes/day in the past year
* Be interested in making a quit attempt in the next 30 days
* Own a smartphone (apple/android)
* Read/speak English
* Able to consent
* Have no plans to move in the next 3 months
* Are not pregnant or planning to be pregnant in the following 3 months

Exclusion Criteria

* Have contraindication to NRT (past month myocardial infarction, history of serious arrhythmias/or unstable angina pectoris, dermatological disorder)
* Are currently being treated for a psychiatric condition
* Are currently being treated for smoking cessation, alcoholism, or illicit drug use
* Are adults unable to consent
* Are individuals who are not yet adults
* Are pregnant women
* Are prisoners
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Taghrid Asfar

Research Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Taghrid Asfar, MD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami

Miami, Florida, United States

Site Status

St. Jude Children's Research Hospital

Memphis, Tennessee, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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20190328

Identifier Type: -

Identifier Source: org_study_id

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