Blood-Flow Restriction Exercise Following a Knee Replacement
NCT ID: NCT04018638
Last Updated: 2024-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
30 participants
INTERVENTIONAL
2019-06-25
2025-12-25
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Adults with TKR Perform Home Exercise Program
Participants that have a total knee replacement will complete a home-based exercise program
B-FREE
Blood flow-restriction exercise enhancement (B-FREE) will be performed at home 3x/wk for 10 weeks. A blood pressure cuff will be inflated to partially occlude blood to the limb during light weight exercises involving knee extension, body weight squats, and walking.
Healthy Controls Only
Participants that have no history of knee joint dysfunction will serve as age-matched uninjured controls
No interventions assigned to this group
Interventions
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B-FREE
Blood flow-restriction exercise enhancement (B-FREE) will be performed at home 3x/wk for 10 weeks. A blood pressure cuff will be inflated to partially occlude blood to the limb during light weight exercises involving knee extension, body weight squats, and walking.
Eligibility Criteria
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Inclusion Criteria
* Have had a unilateral TKA \> 6 months prior to participation (Arm 1)
* No previous history of knee injury/surgery (Arm 2)
Exclusion Criteria
* Have diabetes
* Have suffered a heart attack or stroke
* Have any cardiopulmonary disorders (hypertension discussed below)
* Have been diagnosed with any neurological disorders
* Have any implanted devices such as but not limited to a pacemaker or pain pump
* Uncontrolled (not medicated) Stage 1 hypertension or Stage 2 hypertension
40 Years
75 Years
ALL
Yes
Sponsors
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Blue Cross Blue Shield of Michigan Foundation
OTHER
Michigan Technological University
OTHER
Responsible Party
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Principal Investigators
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Steven Elmer
Role: PRINCIPAL_INVESTIGATOR
Michigan Technological University
Locations
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Michigan Technological University
Houghton, Michigan, United States
Countries
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Other Identifiers
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MichiganTU
Identifier Type: -
Identifier Source: org_study_id