Idiopathic Pulmonary Fibrosis and Serum Bank

NCT ID: NCT04016168

Last Updated: 2023-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

903 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-22

Study Completion Date

2022-12-28

Brief Summary

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Idiopathic pulmonary fibrosis (IPF) is the most common form of chronic idiopathic diffuse interstitial lung disease (DILD) in adults. It is a fibroproliferative, irreversible disease of unknown cause, usually progressive, occurring mainly from the age of 60 and limited to the lungs. IPF is a serious disease with a median survival rate at diagnosis of 3 years.

The aim of the study is to set up a biocollection of serum from patients in a context of idiopathic DILD and a possible or confirmed diagnosis of common interstitial lung disease by chest CT.

Patients will be recruited at the consultations of the Rennes Rare Lung Disease Competence Centre. These will be patients in stable condition or in acute exacerbation of IPF.

Detailed Description

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This study will initially focus on circulating serum CD163 markers, but a broader proteomics approach could be considered in a second phase to look for other markers of lung diseases.

Conditions

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Idiopathic Pulmonary Fibrosis Lung Diseases, Interstitial

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with DILD

Patients will be recruited at the consultations of the Rennes Rare Lung Disease Competence Centre. These will be patients in stable condition or in acute exacerbation of IPF.

Blood sample collection

Intervention Type BIOLOGICAL

Three additional blood tubes (3 x 8mL) will be collected for this study. They will be added to the traditional diagnostic assessment carried out for their IPF, during their consultation at the competence centre for rare lung diseases. These samples will be taken by a registered nurse in the presence and under the responsibility of the investigator.

Interventions

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Blood sample collection

Three additional blood tubes (3 x 8mL) will be collected for this study. They will be added to the traditional diagnostic assessment carried out for their IPF, during their consultation at the competence centre for rare lung diseases. These samples will be taken by a registered nurse in the presence and under the responsibility of the investigator.

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Patients seen on an outpatient basis and in stable or acute condition
* Patient over 18 years of age.

Exclusion Criteria

* Patients who are unable or unwilling to sign the consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rennes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stéphane JOUNEAU, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital of Rennes

Locations

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Rennes University Hospital - Service de Pneumologie

Rennes, , France

Site Status

Countries

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France

Other Identifiers

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2014-A00268-39

Identifier Type: OTHER

Identifier Source: secondary_id

35RC14_9722

Identifier Type: -

Identifier Source: org_study_id