Trial Outcomes & Findings for Investigating the Effects of a Spinal Mobilisation Intervention in People With Lower Back Pain (NCT NCT04012970)

NCT ID: NCT04012970

Last Updated: 2019-11-29

Results Overview

Stiffness values measured before and after 30 minute spinal mobilisation intervention. Location of muscle assessed by palpation by asking participant to contract lower back muscles and marking the central belly of the muscle. Myometer measurements recorded using handheld device MyotonPRO held over marked area. Recorded 3 times and mean value used for analysis.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

40 participants

Primary outcome timeframe

Change in muscle stiffness immediately after the 30 minute spinal mobilisation intervention.

Results posted on

2019-11-29

Participant Flow

Participant milestones

Participant milestones
Measure
A - Intervention Then Control
Intervention (30 minutes spinal mobilisations) received in first session, control (30 minutes lying still) received in second session.
B - Control Then Intervention
Control (30 minutes lying still) received in first session, then intervention (30 minutes spinal mobilisations) received in second session.
Intervention Session, 30 Minutes
STARTED
26
14
Intervention Session, 30 Minutes
COMPLETED
26
14
Intervention Session, 30 Minutes
NOT COMPLETED
0
0
Control Session, 30 Minutes
STARTED
26
14
Control Session, 30 Minutes
COMPLETED
26
14
Control Session, 30 Minutes
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
A - Intervention Then Control
n=26 Participants
Intervention (30 minutes spinal mobilisations) received in first session, then control (30 minutes lying still) received in second session.
B - Control Then Intervention
n=14 Participants
Control (30 minutes lying still) received in first session, then intervention (30 minutes spinal mobilisations) received in second session.
Total
n=40 Participants
Total of all reporting groups
Age, Continuous
32.73 years
STANDARD_DEVIATION 12.99 • n=26 Participants
28 years
STANDARD_DEVIATION 6.92 • n=14 Participants
31.075 years
STANDARD_DEVIATION 11.373 • n=40 Participants
Sex: Female, Male
Female
13 Participants
n=26 Participants
9 Participants
n=14 Participants
22 Participants
n=40 Participants
Sex: Female, Male
Male
13 Participants
n=26 Participants
5 Participants
n=14 Participants
18 Participants
n=40 Participants
Race and Ethnicity Not Collected
0 Participants
Race and Ethnicity were not collected from any participant.

PRIMARY outcome

Timeframe: Change in muscle stiffness immediately after the 30 minute spinal mobilisation intervention.

Stiffness values measured before and after 30 minute spinal mobilisation intervention. Location of muscle assessed by palpation by asking participant to contract lower back muscles and marking the central belly of the muscle. Myometer measurements recorded using handheld device MyotonPRO held over marked area. Recorded 3 times and mean value used for analysis.

Outcome measures

Outcome measures
Measure
Intervention
n=40 Participants
Group A and Group B results for stiffness change due to the spinal mobilisation intervention.
Intervention Erector Spinae Stiffness Change
-10.959 Newton metres (Nm)
Standard Error 4.132

PRIMARY outcome

Timeframe: Change in muscle stiffness immediately after the 30 minute control session (lying still).

Stiffness values measured before and after 30 minute control lying still. Location of muscle assessed by palpation by asking participant to contract lower back muscles and marking the central belly of the muscle. Myometer measurements recorded using handheld device MyotonPRO held over marked area. Recorded 3 times and mean value used for analysis.

Outcome measures

Outcome measures
Measure
Intervention
n=40 Participants
Group A and Group B results for stiffness change due to the spinal mobilisation intervention.
Control Erector Spinae Stiffness Change.
12.192 Newton metres (Nm)
Standard Error 4.023

SECONDARY outcome

Timeframe: Change in muscle tone immediately after the 30 minute spinal mobilisation intervention.

Tone values measured before and after 30 minute spinal mobilisation intervention. Location of muscle assessed by palpation by asking participant to contract lower back muscles and marking the central belly of the muscle. Myometer measurements recorded using handheld device MyotonPRO held over marked area. Recorded 3 times and mean value used for analysis.

Outcome measures

Outcome measures
Measure
Intervention
n=40 Participants
Group A and Group B results for stiffness change due to the spinal mobilisation intervention.
Intervention Erector Spinae Tone Change
-0.317 Hertz (Hz)
Standard Error 0.088

SECONDARY outcome

Timeframe: Change in muscle tone immediately after the 30 minute control session (lying still).

Tone values measured before and after 30 minute control lying still. Location of muscle assessed by palpation by asking participant to contract lower back muscles and marking the central belly of the muscle. Myometer measurements recorded using handheld device MyotonPRO held over marked area. Recorded 3 times and mean value used for analysis.

Outcome measures

Outcome measures
Measure
Intervention
n=40 Participants
Group A and Group B results for stiffness change due to the spinal mobilisation intervention.
Control Erector Spinae Tone Change
0.29 Hertz (Hz)
Standard Error 0.1

SECONDARY outcome

Timeframe: Change in muscle elasticity immediately after the 30 minute spinal mobilisation intervention.

Elasticity values measured before and after 30 minute spinal mobilisation intervention. Location of muscle assessed by palpation by asking participant to contract lower back muscles and marking the central belly of the muscle. Myometer measurements recorded using handheld device MyotonPRO held over marked area. The device records the logarithmic decrement of the tissue by recording the dissipation of the mechanical energy of the tissue when it recovers shape after deformation. Elasticity is then inversely proportional to the decrement, so a higher decrement value equates to a higher dissipation of mechanical energy and a lower elasticity value. Recorded 3 times and mean value used for analysis.

Outcome measures

Outcome measures
Measure
Intervention
n=40 Participants
Group A and Group B results for stiffness change due to the spinal mobilisation intervention.
Intervention Erector Spinae Elasticity Change
0.068 Logarithmic decrement
Standard Error 0.02

SECONDARY outcome

Timeframe: Change in muscle elasticity immediately after the 30 minute control session (lying still).

Elasticity values measured before and after 30 minute control lying still. Location of muscle assessed by palpation by asking participant to contract lower back muscles and marking the central belly of the muscle. Myometer measurements recorded using handheld device MyotonPRO held over marked area. The device records the logarithmic decrement of the tissue by recording the dissipation of the mechanical energy of the tissue when it recovers shape after deformation. Elasticity is then inversely proportional to the decrement, so a higher decrement value equates to a higher dissipation of mechanical energy and a lower elasticity value. Recorded 3 times and mean value used for analysis.

Outcome measures

Outcome measures
Measure
Intervention
n=40 Participants
Group A and Group B results for stiffness change due to the spinal mobilisation intervention.
Control Erector Spinae Elasticity Change
0.05 Logarithmic decrement
Standard Error 0.012

Adverse Events

Group A - Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Group A - Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Group B - Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Group B - Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Rebecca Hamilton, PhD student

Edinburgh Napier Univerisity

Phone: 0131 455

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place