The Evaluation of a New Nasal Mask for the Treatment of Obstructive Sleep Apnea

NCT ID: NCT04011826

Last Updated: 2021-12-01

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-08-05

Study Completion Date

2020-08-30

Brief Summary

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This investigation is designed to evaluate the comfort, ease of use and performance of a trial nasal mask for the treatment of Obstructive Sleep Apnea (OSA) in the home environment.

Detailed Description

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The investigation is a prospective, non-randomized, non-blinded study. Up to 45 OSA participants who currently use a nasal, sub-nasal or pillows mask will be recruited.

The study will involve a baseline (Visit 1) data gathering with the participant's PAP therapy and their usual mask. This will be followed by the participants being fitted with the trial nasal mask by a mask fitting expert for use in-home (Visit 2). There will be a follow up phone call to gain feedback or address any issues after 3±1 days. The participant will then come in to return the mask (Visit 3) and give feedback on their experience using the mask in home in the form of a structured interview during Visit 3. If the participants prefer the trail nasal mask they will be asked if they would like to continue using the trial mask for a further six months in-home. There will be a follow up monthly phone call to gain feedback or address any issues during the extension. At the end of the six month extension period, the participants will return the trial nasal mask to the institution and give feedback on their experience using the mask in home in the form of a self-administered questionnaire. Participants will revert to their usual masks thereafter. Neither the participants nor the investigators will be blinded to the study.

Conditions

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Obstructive Sleep Apnea

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

After a period of baseline, all enrolled participants will be put on the same trial mask.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Experimental: Experimental trial nasal mask

Experimental trial nasal mask: Participants will be placed on this arm for a total of 14±3 days from Visit 2. Participants will be using the trial nasal mask during this treatment arm. Participants on the extension will use this trial mask for a further six months after Visit 3.

Group Type EXPERIMENTAL

Device: Trial nasal mask (F&P)

Intervention Type DEVICE

This trial nasal mask will serve as the participant's primary PAP/BPAP therapy mask for the duration of the trial period (from Visit 2 to Visit 3). For participants taking part in the study extension, they will be using the trial nasal mask as their primary PAP/BPAP therapy mask for 6 months after Visit 3.

Interventions

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Device: Trial nasal mask (F&P)

This trial nasal mask will serve as the participant's primary PAP/BPAP therapy mask for the duration of the trial period (from Visit 2 to Visit 3). For participants taking part in the study extension, they will be using the trial nasal mask as their primary PAP/BPAP therapy mask for 6 months after Visit 3.

Intervention Type DEVICE

Other Intervention Names

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New nasal mask

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of OSA by Physician
* ≥ 22 years of age
* ≥ 66 lbs
* Prescribed PAP or BPAP therapy for OSA
* Existing nasal, sub-nasal and pillows mask users
* Fluent in written and spoken English

Exclusion Criteria

* Inability to give informed consent
* Pregnant or think they may be pregnant
* PAP Intolerant
* Anatomical or Physiological Conditions that make PAP inappropriate
* IPAP pressure of ≤25cmH20.
* PAP/BPAP therapy device without data recording capabilities
* Using a PAP/BPAP therapy device for the delivery any medication with the exception of oxygen
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fisher and Paykel Healthcare

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mark Muehlbach

Role: PRINCIPAL_INVESTIGATOR

Clinical Director

Locations

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Clayton Sleep Institute

St Louis, Missouri, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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CIA-262

Identifier Type: -

Identifier Source: org_study_id