Planning Your Everyday Life in Virtual Reality : a Study in Schizophrenia;

NCT ID: NCT04011774

Last Updated: 2022-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

144 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-09

Study Completion Date

2024-08-09

Brief Summary

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Patients with schizophrenia , who visit frenquently day-care or day-care activities clinics, often experience difficulties of daily living and cognitive deficits. Living independently is a key for recovery. Cognitive remediation is a therapy which reduces deficit and improves daily living. Nowadays no program exists targeting neurocognitive functions in virtual reality which could mimic everyday life in a virtual town.

Hypotheses :

* Persons with schizophrenia experience difficulties in daily living and disabilities to plan in everyday life. PLANI-REV program, a serious game with a navigation in a virtual town, in a 15 weekly group sessions could reduce these difficulties compared to the initial assessment. This improvement could be maintained 6 months after the end of the program.
* PLANI-REV could also improve prospective memory, attention, working memory, and visuospatial organization.
* PLANI-REV could induce a clinical improvement, as well as better perception of self-efficiency, self esteem, quality of life, and conversation skills.

Detailed Description

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Conditions

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Schizophrenia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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PLANI-REV

Persons with schizophrenia who will benefit from the fifteen weekly sessions of PLANI-REV group program

Group Type EXPERIMENTAL

PLANI-REV

Intervention Type OTHER

Cognitive remediation program.

RELAXATION

Persons with schizophrenia who will benefit from a non cognitive stimulation, namely RELAXATION, in a day-care clinic or day-care therapeutic activities center during fifteen weekly sessions. This activity will be 15 groups sessions of relaxation.

Group Type ACTIVE_COMPARATOR

RELAXATION

Intervention Type OTHER

Stimulation with no cognitive remediation.

Interventions

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PLANI-REV

Cognitive remediation program.

Intervention Type OTHER

RELAXATION

Stimulation with no cognitive remediation.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 50 years old.
* Diagnostic of schizophrenia or schizoaffective disorder (DSM V), attested by the MINI structured interview (Shehan et al. 1998)
* Who visit for months or year, weekly or several times per week, a day care, or therapeutic activity units outpatients clinics and nursing homes
* French Mother tongue
* Consent of the legal representative caregiver for the patients under representative law (tutelle in French).
* Clinical Stability - Therapeutic stability for at least one month.
* National healthcare assurance

Exclusion Criteria

* Central Neurological or non stabilized somatic diseases.
* Treatments for somatic disease with putative psychotropic effect.
* Electroconvulsive therapy in the last six months
* Illetrism
* IQ\< 70 established with the f-NART.
* Substance misuse or dependence (except Nicotine) or toxic for more than 5 years.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier St Anne

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Isabelle AMADO, MD

Role: PRINCIPAL_INVESTIGATOR

CHSA

Locations

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Centre Hospitalier DURANT

Étampes, , France

Site Status RECRUITING

Hopital les Murets

La Queue-en-Brie, , France

Site Status RECRUITING

Centre Hospitalier Sainte Anne

Paris, , France

Site Status RECRUITING

Centre Hospitalier Guillaume Régnier

Rennes, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Isabelle AMADO, MD

Role: CONTACT

Phone: +33 1 45 65 81 80

Email: [email protected]

Sylvie DOROCANT

Role: CONTACT

Phone: +33 1 45 65 77 28

Email: [email protected]

Facility Contacts

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François PETITJEAN, MD

Role: primary

Olivier QUENZER, MD

Role: primary

Isabelle AMADO, MD

Role: primary

Sylvie DOROCANT

Role: backup

David LEVOYER, MD

Role: primary

Other Identifiers

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D17-P025

Identifier Type: -

Identifier Source: org_study_id