Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity

NCT ID: NCT04005417

Last Updated: 2019-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1036 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-08

Study Completion Date

2018-11-30

Brief Summary

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The aim of this 11 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) on dentine hypersensitivity versus a positive or negative control dentifrice.

Detailed Description

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Conditions

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Dentine Hypersensitivity

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Stannous fluoride dentifrice

Twice daily brushing

Stannous fluoride dentifrice

Intervention Type DRUG

Stannous fluoride (0.454%) dentifrice

Positive control dentifrice

Twice daily brushing

Positive control dentifrice

Intervention Type DRUG

Positive control dentifrice containing potassium nitrate or arginine.

Negative control dentifrice

Twice daily brushing

Negative control dentifrice

Intervention Type DRUG

Negative control dentifrice containing either sodium fluoride (0.243%) or sodium monofluorophosphate (0.76%)

Interventions

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Stannous fluoride dentifrice

Stannous fluoride (0.454%) dentifrice

Intervention Type DRUG

Positive control dentifrice

Positive control dentifrice containing potassium nitrate or arginine.

Intervention Type DRUG

Negative control dentifrice

Negative control dentifrice containing either sodium fluoride (0.243%) or sodium monofluorophosphate (0.76%)

Intervention Type DRUG

Eligibility Criteria

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Exclusion Criteria

* severe periodontitis
* at discretionary of the Principal Investigator
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Procter and Gamble

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Multiple P&G Investigation Clinical Sites

Cincinnati, Ohio, United States

Site Status

Countries

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United States

Other Identifiers

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2019SnF2SensitivityAnalysis

Identifier Type: -

Identifier Source: org_study_id

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