Specified Drug-Use Survey on Vedolizumab for IV Infusion 300 mg [Crohn's Disease]

NCT ID: NCT04002180

Last Updated: 2026-01-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

335 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-07-01

Study Completion Date

2026-06-30

Brief Summary

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The purpose of this survey is to evaluate the long-term safety and effectiveness of vedolizumab for intravenous (IV) infusion 300 milligrams (mg) in Crohn's disease (CD) patients in the routine clinical setting.

Detailed Description

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The drug being tested in this survey is called vedolizumab for IV infusion 300 mg. This drug is being tested to treat patients who have CD.

This survey is an observational (non-interventional) study and will look at the long-term safety and effectiveness of vedolizumab for IV infusion 300 mg in the routine clinical setting. The planned number of observed patients will be approximately 300.

This multi-center observational trial will be conducted in Japan.

Conditions

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Crohn's Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Vedolizumab 300 mg

Vedolizumab (Genetical Recombination) 300 mg, IV infusion, at Weeks 0, 2 and 6, and every 8 weeks thereafter, for up to 54 weeks. Participants will receive IV infusion as part of routine medical care.

Vedolizumab (Genetical Recombination)

Intervention Type DRUG

Vedolizumab IV infusion

Interventions

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Vedolizumab (Genetical Recombination)

Vedolizumab IV infusion

Intervention Type DRUG

Other Intervention Names

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Entyvio for IV Infusion 300 mg

Eligibility Criteria

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Inclusion Criteria

1. Have moderate or severe active CD
2. Have inadequate response to existing therapies

Exclusion Criteria

Patients with any contraindication for vedolizumab
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Takeda

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Study Director

Role: STUDY_DIRECTOR

Takeda

Locations

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Takeda Selected Site

Tokyo, , Japan

Site Status

Countries

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Japan

Related Links

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https://clinicaltrials.takeda.com/study-detail/5f6b603c4db2bf003ab4a339

To obtain more information on the study, click here/on this link

Other Identifiers

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jRCT1080224753

Identifier Type: REGISTRY

Identifier Source: secondary_id

Vedolizumab-4021

Identifier Type: -

Identifier Source: org_study_id

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