NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration
NCT ID: NCT03997552
Last Updated: 2024-12-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
60 participants
INTERVENTIONAL
2019-09-06
2025-12-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Non-incised papillae surgical approach (NIPSA)
To access the defect, a single horizontal or oblique apical incision will be made in the mucosa located on the bony cortex, far from the marginal tissues and apically to the edge of the bony crest delimiting the defect. The incision will be extended mesiodistally as necessary to allow access to the defect and correct debridement of the granulation tissue. The tissue coronal to the incision will be raised full thickness, trying to maintain the preoperative papillae architecture intact. The granulation tissue and epithelium of the pocket will be eliminated. The affected root will be scaled and planed, and calculus eliminated. Once the defect will be debrided, the enamel matrix derivates will be applied. Then the incision line will be sutured by a double suture line to facilitate closing without tension: The first with internal horizontal mattress sutures to approximate the connective tissue of both edges of the mucosal incision, and the second with single interrupted sutures.
Non-incised papillae surgical approach (NIPSA)
Periodontal reconstructive surgery
marginal approach by palatal incision
A small incision in the palatal aspect and a limited papila elevation to the buccal aspect will be made for treating isolated periodontal defect. Enamel matrix derivates will be applied on the debrided root surfaces.
marginal approach by palatal incision
Periodontal reconstructive surgery
Minimally invasive surgical technique (MIST)
The incision of the defect-associated papilla will be performed according to the principles of the papilla preservation techniques. Enamel matrix derivates will be applied on the debrided root surfaces. Stable primary closure of the flaps will be obtained with internal modified mattress sutures.
Minimally invasive surgical technique (MIST)
Periodontal reconstructive surgery
Interventions
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Non-incised papillae surgical approach (NIPSA)
Periodontal reconstructive surgery
marginal approach by palatal incision
Periodontal reconstructive surgery
Minimally invasive surgical technique (MIST)
Periodontal reconstructive surgery
Eligibility Criteria
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Inclusion Criteria
* plaque index and bleeding index of \< 30%.
* periodontal lesions with pocket probing depth \> 5 mm.
* intrabony defect \> 3 mm.
* intrabony defect configuration including a 1 and/or 2-wall component, always involving the buccal wall.
Exclusion Criteria
* third molars.
* teeth with incorrect endodontic or restorative treatment.
18 Years
ALL
No
Sponsors
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Universidad de Murcia
OTHER
Responsible Party
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Antonio José Ortiz Ruiz, MD
Professor and researcher
Locations
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Centro Odontologico Del Sureste Slp
Murcia, , Spain
Countries
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Central Contacts
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Facility Contacts
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Antonio J Ortiz-Ruiz, MD
Role: primary
Jose A Moreno-Rodriguez
Role: backup
References
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Moreno Rodriguez JA, Ortiz Ruiz AJ, Caffesse RG. Periodontal reconstructive surgery of deep intraosseous defects using an apical approach. Non-incised papillae surgical approach (NIPSA): A retrospective cohort study. J Periodontol. 2019 May;90(5):454-464. doi: 10.1002/JPER.18-0405. Epub 2018 Nov 28.
Moreno Rodriguez JA, Ortiz Ruiz AJ, Caffesse RG. Supra-alveolar attachment gain in the treatment of combined intra-suprabony periodontal defects by non-incised papillae surgical approach. J Clin Periodontol. 2019 Sep;46(9):927-936. doi: 10.1111/jcpe.13158. Epub 2019 Jul 22.
Other Identifiers
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2409/2019
Identifier Type: -
Identifier Source: org_study_id