Outcomes After Hypotensive Neuraxial Anesthesia in Total Hip Arthroplasty
NCT ID: NCT03973320
Last Updated: 2024-12-27
Study Results
Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.
View full resultsBasic Information
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COMPLETED
11292 participants
OBSERVATIONAL
2018-12-27
2019-11-18
Brief Summary
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Detailed Description
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Primary outcomes:
Multiple logistic regression will be used to compute the adjusted odds ratios of any postoperative complications (MI, CVA, death) , adjusting for covariates including duration of intraoperative mean arterial pressure of less than pre-defined threshold, such as 55, or 60 mmHg mean blood pressure.
Sensitivity analyses will also consider the effects of intra-operative hypotension (IOH) defined as mean blood pressure of less than 40, 45, 50, 55, 60, and 65 mm Hg.
Secondary outcomes:
Multiple logistic regression will be to compute the adjusted odds ratios of individual postoperative complications, (such as MI, CVA, stroke) , adjusting for covariates including duration of intraoperative mean blood pressure of less than pre-defined threshold, such as 55, or 60 mmHg mean blood pressure. Sensitivity analyses will also be conducted to test the effects of extend of IOH on complications.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Primary Total Hip Arthroplasty
This is a chart review to determine if hypotensive neuraxial anesthesia is associated with worse outcomes in Primary Total Hip Arthroplasty
Chart Review
This is a chart review to determine if hypotensive neuraxial anesthesia is associated with worse outcomes in Primary Total Hip Arthroplasty patients.
Interventions
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Chart Review
This is a chart review to determine if hypotensive neuraxial anesthesia is associated with worse outcomes in Primary Total Hip Arthroplasty patients.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Incomplete intraoperative vital signs
* Anterior total hip arthroplasty
18 Years
ALL
No
Sponsors
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Hospital for Special Surgery, New York
OTHER
Responsible Party
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Principal Investigators
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Jiabin Liu, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Hospital for Special Surgey
Locations
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Hospital for Special Surgery
New York, New York, United States
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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2018-2235
Identifier Type: -
Identifier Source: org_study_id