Clinical and Radiological Evaluation of Meniscal Healing After Percutaneous Intra-meniscal Injection of Platelet-rich Plasma (PRP)

NCT ID: NCT03966638

Last Updated: 2022-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-11-01

Study Completion Date

2020-11-30

Brief Summary

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Meniscal lesions are a common pathology among athletes, and have an impact on the daily or sporting practice of patients. The consequences of surgical treatment are sometimes heavy.

Platelet-rich-plasma (PRP) has been shown to be effective in healing tendon and ligament lesions.

PRP has been injected under ultrasound in tendons or intra-articularly for several years.

This technique of meniscal percutaneous injection of PRP is now carried out for more than 2 years in our hospital, with satisfactory preliminary results, without any complication.

All patients in our study received an intra-meniscal injection of PRP, under echographic control. They were evaluated clinically and by Magnetic Resonance Imaging (MRI) before and at 6 months of the injection.

The aim of the study is to evaluate the efficacy of intra-meniscal injection of PRP on the symptomatology of the patients (pain, sport activities and daily life) at 6 months post-treatment.

Detailed Description

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Conditions

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Meniscus Lesion

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients receiving platelet rich plasma

The group is composed of patients receiving an intra-meniscal injection of platelet-rich plasma, under echographic control, for isolated meniscal lesion.

Intra-meniscal injection of platelet-rich plasma

Intervention Type PROCEDURE

Intra-meniscal injection of platelet-rich plasma under echographic control

Interventions

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Intra-meniscal injection of platelet-rich plasma

Intra-meniscal injection of platelet-rich plasma under echographic control

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* isolated symptomatic meniscal lesion
* lesion confirmed by MRI
* grade II or III lesion touching the peripheral involvement of the middle segment,
* lesion treated by percutaneous intra meniscal PRP's injection
* IKDC score measured before injection and 6 months post-injection

Exclusion Criteria

* other painful etiology of the knee
* emergency surgical management (luxation, bucket handle) or not (indication validated by the surgeon, meniscectomy or meniscal suture)
* impossibility to perform the procedure (non visible lesion, morphology of the patient, cutaneous infection, coagulation treatment in progress)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Radiology, Croix-Rousse Hospital, Hospices Civils de Lyon

Lyon, , France

Site Status

Countries

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France

Other Identifiers

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CRC_GHN_2019_006

Identifier Type: -

Identifier Source: org_study_id

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