Cognitive Rehabilitation in Older Adults With Neuron-up (CROAN)

NCT ID: NCT03944135

Last Updated: 2019-05-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-15

Study Completion Date

2019-02-20

Brief Summary

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Introduction. The application of new technologies for cognitive rehabilitation has increased over the last years and has enabled occupational therapists to work more efficiently, minimizing costs and time for analysis, management, and design of activities.

Objective. The purpose of the present study was to assess the effect of cognitive intervention using the web platform Neuronup in a group of elderly subjects; the study is based on the dependent variables (memory, attention, and language) analyzed with the abbreviated Barcelona Test.

Subjects and Methods. Aquasi-experimental design was carried out with subjects assigned to two groups: a control group (20 subjects) and an experimental group (20 subjects). The abbreviated Barcelona Test was administered to assess patients before and after the intervention with this software to draw conclusions.

Detailed Description

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Introduction. The application of new technologies for cognitive rehabilitation has increased over the last years and has enabled occupational therapists to work more efficiently, minimizing costs and time for analysis, management, and design of activities.

Objective. The purpose of the present study was to assess the effect of cognitive intervention using the web platform Neuronup in a group of elderly subjects; the study is based on the dependent variables (memory, attention, and language) analyzed with the abbreviated Barcelona Test.

Subjects and Methods. Aquasi-experimental design was carried out with subjects assigned to two groups: a control group (20 subjects) and an experimental group (20 subjects). The abbreviated Barcelona Test was administered to assess patients before and after the intervention with this software to draw conclusions.

Results. Analyses of variance (ANOVA), analyses of covariance (ANCOVA), and multivariate analyses of variance (MANOVA) were perfomed in the memory, orientation, reading, and language domains. Statistically signifcant differences were recorded in all domains except language where scores remained the same.

Conclusion. It has been demonstrated that Neuronup is an effective program for improving cognitive processes such as memory, attention, and orientation in older adults, hence it would be beneficial to implement technology-based treatments conducted by specialized professionals.

Conditions

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Indication for Modification of Patient Cognitive Status

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

This is a quasi-experimental design with non-equivalent groups (pretest-posttest) carried out in a more realistic setting, where the dependent variables of interest were manipulated by the researcher under controlled conditions.
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Investigators

Study Groups

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Experimental group

The sample consisted of 40 people: 20 in an experimental group. There were 5 men and 15 women.

Group Type EXPERIMENTAL

Web platform: Neuronup

Intervention Type OTHER

Neuronup is a web platform designed for neuropsychological rehabilitation that is focused on functional cognitive impairments resulting from normal aging and other causes. Neuronup emerged as a scientific, viable and accessible technological initiative.

Control group

The sample consisted of 40 people: 20 in a control group. There were 5 men and 15 women.

Group Type ACTIVE_COMPARATOR

Web platform: Neuronup

Intervention Type OTHER

Neuronup is a web platform designed for neuropsychological rehabilitation that is focused on functional cognitive impairments resulting from normal aging and other causes. Neuronup emerged as a scientific, viable and accessible technological initiative.

Interventions

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Web platform: Neuronup

Neuronup is a web platform designed for neuropsychological rehabilitation that is focused on functional cognitive impairments resulting from normal aging and other causes. Neuronup emerged as a scientific, viable and accessible technological initiative.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. subjects between 75 and 85 years of age;
2. obtain a score greater than 20 points for the MEC (Lobo's cognitive mini-exam); and
3. attend occupational therapy sessions on a regular basis.

Exclusion Criteria

1. presence of neurocognitive disorder (Alzheimer's-type dementia among others);
2. not be an institutionalized resident at a nursing home;
3. a family history of a psychiatric problem;
4. presence of polipathology; and
5. have lived at a nursing home for less than 2 months.
Minimum Eligible Age

75 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad de Burgos

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Olalla Saiz Vazquez

Role: PRINCIPAL_INVESTIGATOR

Universidad de Burgos

Locations

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Olalla Saiz Vazquez

Burgos, , Spain

Site Status

Countries

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Spain

References

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Mohs RC, Ashman TA, Jantzen K, Albert M, Brandt J, Gordon B, Rasmusson X, Grossman M, Jacobs D, Stern Y. A study of the efficacy of a comprehensive memory enhancement program in healthy elderly persons. Psychiatry Res. 1998 Feb 27;77(3):183-95. doi: 10.1016/s0165-1781(98)00003-1.

Reference Type BACKGROUND
PMID: 9707301 (View on PubMed)

Dellefield KS, McDougall GJ. Increasing metamemory in older adults. Nurs Res. 1996 Sep-Oct;45(5):284-90. doi: 10.1097/00006199-199609000-00006.

Reference Type BACKGROUND
PMID: 8831655 (View on PubMed)

Wilkinson AJ, Yang L. Long-Term Maintenance of Inhibition Training Effects in Older Adults: 1- and 3-Year Follow-Up. J Gerontol B Psychol Sci Soc Sci. 2016 Jul;71(4):622-9. doi: 10.1093/geronb/gbu179. Epub 2015 Jan 7.

Reference Type BACKGROUND
PMID: 25573153 (View on PubMed)

Neely AS, Backman L. Effects of multifactorial memory training in old age: generalizability across tasks and individuals. J Gerontol B Psychol Sci Soc Sci. 1995 May;50(3):P134-40. doi: 10.1093/geronb/50b.3.p134.

Reference Type BACKGROUND
PMID: 7767691 (View on PubMed)

Lachman ME, Weaver SL, Bandura M, Elliott E, Lewkowicz CJ. Improving memory and control beliefs through cognitive restructuring and self-generated strategies. J Gerontol. 1992 Sep;47(5):P293-9. doi: 10.1093/geronj/47.5.p293.

Reference Type BACKGROUND
PMID: 1512434 (View on PubMed)

Valentijn SA, van Hooren SA, Bosma H, Touw DM, Jolles J, van Boxtel MP, Ponds RW. The effect of two types of memory training on subjective and objective memory performance in healthy individuals aged 55 years and older: a randomized controlled trial. Patient Educ Couns. 2005 Apr;57(1):106-14. doi: 10.1016/j.pec.2004.05.002.

Reference Type BACKGROUND
PMID: 15797159 (View on PubMed)

Floyd M, Scogin F. Effects of memory training on the subjective memory functioning and mental health of older adults: a meta-analysis. Psychol Aging. 1997 Mar;12(1):150-61. doi: 10.1037//0882-7974.12.1.150.

Reference Type BACKGROUND
PMID: 9100276 (View on PubMed)

Valencia C, Lopez-Alzate E, Tirado V, Zea-Herrera MD, Lopera F, Rupprecht R, Oswald WD. [Cognitive effects of combined memory and psychomotor training in elderly adults]. Rev Neurol. 2008 Apr 16-30;46(8):465-71. Spanish.

Reference Type BACKGROUND
PMID: 18428103 (View on PubMed)

E Mintzer J, F Mirski D, S Hoernig K. Behavioral and psychological signs and symptoms of dementia: a practicing psychiatrist's viewpoint. Dialogues Clin Neurosci. 2000 Jun;2(2):139-55. doi: 10.31887/DCNS.2000.2.2/jmintzer.

Reference Type BACKGROUND
PMID: 22034243 (View on PubMed)

Valdizan JR. [Cognitive functions and neuronal networks in the social brain]. Rev Neurol. 2008;46 Suppl 1:S65-8. Spanish.

Reference Type BACKGROUND
PMID: 18302126 (View on PubMed)

Rey Cao A, Canales Lacruz I, Taboas Pais MI. [Quality of life perceived by the elderly. Results of the "Memory in movement" program which provide cognitive stimulation using motricity]. Rev Esp Geriatr Gerontol. 2011 Mar-Apr;46(2):74-80. doi: 10.1016/j.regg.2010.08.005. Epub 2011 Mar 25. Spanish.

Reference Type RESULT
PMID: 21440332 (View on PubMed)

Wenisch E, Cantegreil-Kallen I, De Rotrou J, Garrigue P, Moulin F, Batouche F, Richard A, De Sant'Anna M, Rigaud AS. Cognitive stimulation intervention for elders with mild cognitive impairment compared with normal aged subjects: preliminary results. Aging Clin Exp Res. 2007 Aug;19(4):316-22. doi: 10.1007/BF03324708.

Reference Type RESULT
PMID: 17726363 (View on PubMed)

Jean L, Bergeron ME, Thivierge S, Simard M. Cognitive intervention programs for individuals with mild cognitive impairment: systematic review of the literature. Am J Geriatr Psychiatry. 2010 Apr;18(4):281-96. doi: 10.1097/JGP.0b013e3181c37ce9.

Reference Type RESULT
PMID: 20220584 (View on PubMed)

Novoa AM, Juarez O, Nebot M. [Review of the effectiveness of cognitive interventions in preventing cognitive deterioration in healthy elderly individuals]. Gac Sanit. 2008 Sep-Oct;22(5):474-82. doi: 10.1157/13126930. Spanish.

Reference Type RESULT
PMID: 19000530 (View on PubMed)

Other Identifiers

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IR 10/2019

Identifier Type: REGISTRY

Identifier Source: secondary_id

UBurgos

Identifier Type: -

Identifier Source: org_study_id

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