Impact of Phone Call About Financial Reimbursement Program on Access to Cancer Clinical Trials

NCT ID: NCT03943082

Last Updated: 2021-11-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

252 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-08

Study Completion Date

2021-10-26

Brief Summary

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This trial studies how well a follow-up phone call regarding financial reimbursement program (FRP) works in improving cancer patients' access to therapeutic cancer clinical trials. Follow-up phone call intervention regarding FRP may improve recruitment of cancer patients to cancer therapeutic clinical trials.

Detailed Description

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There are limited financial models that address the economic hardship associated with clinical research participation and how it might restrict clinical research access. The Lazarex Foundation offers a financial reimbursement program (FRP) to help patients and caregivers cover the out-of-pocket costs associated with clinical trial participation for almost ten years.

iMPACT is a pilot study to assess the overall feasibility of conducting a multi-center trial of the Lazarex sliding scale FRP among sociodemographically diverse patients of all cancer types enrolling/potentially enrolling in therapeutic clinical trials (TCTs). The study will formalize informing patients or parents/legal guardians of patients about the Lazarex sliding-scale FRP in order to evaluate whether operationalizing intensive follow-up about the Lazarex FRP improves recruitment to cancer TCTs.

All patients or parents/legal guardians of patients will be offered information about the FRP at initial time of TCT discussion/consent for the iMPACT study, however, participants will be randomized 1:1 to receive an additional follow-up call about the FRP or no follow-up call (usual care). Participants who are randomized to usual care will be provided a phone number for the Lazarex Foundation that they or their parent or legal guardian may contact directly. Therefore all patients or parents/legal guardians of patients in the study have access to FRP eligibility assessment through the Lazarex Foundation.

Participants or parents/legal guardians of participants will be surveyed at baseline (time of consent to iMPACT) and interviewed 30 days after consent to iMPACT. If a participant enrolls in a therapeutic clinical trial, he/she will also be given an additional survey after TCT participation and interviewed up to 90 days after TCT participation.

Conditions

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Malignant Neoplasm Hematopoietic and Lymphoid Cell Neoplasm

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Cohort A : Usual Care (FRP Only)

Patients or parents/legal guardians of patients receive FRP brochure at the time of iMPACT consent.

Group Type ACTIVE_COMPARATOR

Cancer Educational Materials

Intervention Type BEHAVIORAL

Receive FRP brochure

Questionnaire

Intervention Type BEHAVIORAL

Ancillary studies

Cohort A: Usual Care + Intervention (FRP + Follow-up)

Patients or parents/legal guardians of patients receive FRP brochure at the time of iMPACT consent and a follow-up phone call on day 3 after iMPACT consent.

Group Type EXPERIMENTAL

Cancer Educational Materials

Intervention Type BEHAVIORAL

Receive FRP brochure

Follow-Up Care

Intervention Type OTHER

Receive follow-up phone call

Questionnaire

Intervention Type BEHAVIORAL

Ancillary studies

Interventions

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Cancer Educational Materials

Receive FRP brochure

Intervention Type BEHAVIORAL

Follow-Up Care

Receive follow-up phone call

Intervention Type OTHER

Questionnaire

Ancillary studies

Intervention Type BEHAVIORAL

Other Intervention Names

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Questionnaires

Eligibility Criteria

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Inclusion Criteria

COHORT A:

* Eligible patients to be randomized for the iMPACT study must:

1. Carry a diagnosis of cancer
2. Patient is considered potentially eligible for a cancer therapeutic clinical trial (TCT) and is being offered an opportunity to sign an informed consent document for the cancer TCT
* Eligible patients to receive FRP (these documents will be requested by Lazarex Foundation, however research coordinator at site can help patient collect documents):

1. Have a household income =\< 700% of the 2018 Health and Human Services (HHS) Poverty Guidelines
2. Willing to provide proof of household income. Acceptable proof of income documents are: first two pages of signed copy of income tax return, or if a return is not filed, a copy of the most recent pay stub, unemployment check, Supplemental Security Income (SSI), Social Security Disability (SSD), or public assistance benefit notification. If a patient is not employed, they must submit a signed letter stating their current financial situation
Minimum Eligible Age

7 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Lazarex Cancer Foundation

UNKNOWN

Sponsor Role collaborator

University of California, San Francisco

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hala Borno, MD

Role: PRINCIPAL_INVESTIGATOR

University of California, San Francisco

Locations

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USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States

Site Status

University of California, San Francisco

San Francisco, California, United States

Site Status

Countries

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United States

Other Identifiers

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NCI-2019-00171

Identifier Type: REGISTRY

Identifier Source: secondary_id

189819

Identifier Type: -

Identifier Source: org_study_id